TY - JOUR
T1 - Relapse of ileus in patients with psychiatric disorders
T2 - A 2-year chart review
AU - Kitahata, Ryosuke
AU - Nakajima, Shinichiro
AU - Suzuki, Takefumi
AU - Plitman, Eric
AU - Mimura, Masaru
AU - Uchida, Hiroyuki
N1 - Funding Information:
Dr. Nakajima has received fellowship grants from the Canadian Institutes of Health Research (CIHR) and Japan Society for the Promotion of Science, and manuscript fees from Dainippon Sumitomo Pharma and Kyowa Hakko Kirin. Dr. Suzuki has received speaker or manuscript fees from Astellas, Dainippon Sumitomo, Eli Lilly, Elsevier Japan, Janssen, Novartis, Meiji Seika, Otsuka, and Weily Japan. Dr. Mimura has received grants and/or speaker's honoraria from Asahi Kasei Pharma, Astellas Pharmaceutical, Daiichi Sankyo, Dainippon-Sumitomo Pharma, Eisai, Eli Lilly, GlaxoSmithKline, Janssen Pharmaceutical, Meiji-Seika Pharma, Mochida Pharmaceutical, MSD, Novartis Pharma, Otsuka Pharmaceutical, Pfizer, Shionogi, Takeda, Tanabe Mitsubishi Pharma, and Yoshitomi Yakuhin. Dr. Uchida has received grants from Astellas Pharmaceutical, Eisai, Otsuka Pharmaceutical, GlaxoSmithKline, Shionogi, Dainippon-Sumitomo Pharma, Eli Lilly, Mochida Pharmaceutical, Meiji-Seika Pharma, and Yoshitomi Yakuhin and speaker’s honoraria from Otsuka Pharmaceutical, Eli Lilly, Shionogi, GlaxoSmithKline, Yoshitomi Yakuhin, Dainippon-Sumitomo Pharma, Meiji-Seika Pharma, Abbvie, MSD, and Janssen Pharmaceutical within the past three years. Other authors have no financial or other relationship relevant to the subject of this manuscript.
Publisher Copyright:
© 2016 Elsevier Inc..
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Objective: To explore risk factors for relapse of paralytic ileus in a psychiatric population. Method: We conducted a systematic chart-review to examine two-year relapse rates in psychiatric patients who received treatment for ileus from 2008 to 2012. Binary logistic regression analyses were performed to evaluate associations between sociodemographic and clinical characteristics and relapse of ileus. Results: Sixty-three subjects (38 women; age, 66.0±11.3 years) were included; 62 subjects recovered from ileus. During the subsequent 2 years, 26 (41.3%) subjects experienced relapse. In the entire sample, relapse of ileus was associated with history of abdominal surgery (P = .03, odds ratio=4.34, 95% CI=1.15-16.42) and duration of psychiatric disorders (P = .02, odds ratio=1.00, 95% CI=1.00-1.00). In a subgroup of 43 subjects with schizophrenia, history of abdominal surgery (P = .01, odds ratio=12.09, 95% CI=1.78-82.15) and age (P = .02, odds ratio=1.12, 95% CI=1.02-1.23) predicted relapse of ileus. Conclusions: Since relapse of ileus is common and can be serious in psychiatric patients, special attention is warranted to those who are old, have a history of abdominal surgery or a longer duration of psychiatric disorders to prevent relapse of ileus.
AB - Objective: To explore risk factors for relapse of paralytic ileus in a psychiatric population. Method: We conducted a systematic chart-review to examine two-year relapse rates in psychiatric patients who received treatment for ileus from 2008 to 2012. Binary logistic regression analyses were performed to evaluate associations between sociodemographic and clinical characteristics and relapse of ileus. Results: Sixty-three subjects (38 women; age, 66.0±11.3 years) were included; 62 subjects recovered from ileus. During the subsequent 2 years, 26 (41.3%) subjects experienced relapse. In the entire sample, relapse of ileus was associated with history of abdominal surgery (P = .03, odds ratio=4.34, 95% CI=1.15-16.42) and duration of psychiatric disorders (P = .02, odds ratio=1.00, 95% CI=1.00-1.00). In a subgroup of 43 subjects with schizophrenia, history of abdominal surgery (P = .01, odds ratio=12.09, 95% CI=1.78-82.15) and age (P = .02, odds ratio=1.12, 95% CI=1.02-1.23) predicted relapse of ileus. Conclusions: Since relapse of ileus is common and can be serious in psychiatric patients, special attention is warranted to those who are old, have a history of abdominal surgery or a longer duration of psychiatric disorders to prevent relapse of ileus.
KW - Ileus
KW - Predictor
KW - Psychotropic
KW - Relapse
KW - Schizophrenia
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U2 - 10.1016/j.genhosppsych.2015.09.003
DO - 10.1016/j.genhosppsych.2015.09.003
M3 - Article
C2 - 26589763
AN - SCOPUS:84952872112
VL - 38
SP - 31
EP - 36
JO - General Hospital Psychiatry
JF - General Hospital Psychiatry
SN - 0163-8343
ER -