Relation between blood pressure control, body mass index, and intensity of medical treatment

Ikuo Saito, Kazuko Murata, Hiroshi Hirose, Minako Tsujioka, Hiroshi Kawabe

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A cross-sectional study was performed to assess the rates of blood pressure (BP) control to a systolic goal (<140 mmHg), to a diastolic goal (<90 mmHg), and to both in a sample of 226 treated hypertensive patients. We also examined the association between obesity, BP control, intensity of treatment defined as dose score (summed ranks of doses of all antihypertensive drugs taken), and number of drugs. Of the 226 treated patients (mean age, 60 years; 20.4% women), 67.7% were controlled to the systolic goal, 72.1% were controlled to the diastolic goal, and 53.5% were controlled to both. Patients were divided into four groups according to body mass index (BMI): less than 23, A; 23-24.9, B; 25-26.9, C; and 27 or more, D. There were no differences in the rates of BP control to the systolic goal, to the diastolic goal, or to both among the four groups; however, the dose score and number of drugs administered were higher in patients of group D than in those of the other groups. There was a tendency toward a higher intensity of drug treatment in obese patients with either controlled or uncontrolled BP. The dose score and number of drugs correlated positively with BMI. In representative subgroups (n=62), serum insulin and the homeostasis model assessment value of insulin resistance were higher in the patients in group D than in the other groups. These findings indicate that hypertensive patients managed in a hypertension clinic had satisfactory BP control in 53.5% of cases. A higher intensity of medical treatment is needed to achieve BP control in obese hypertensive patients characterized by insulin resistance.

Original languageEnglish
Pages (from-to)711-715
Number of pages5
JournalHypertension Research
Volume26
Issue number9
DOIs
Publication statusPublished - 2003 Sep 1

Fingerprint

Body Mass Index
Blood Pressure
Therapeutics
Pharmaceutical Preparations
Insulin Resistance
Antihypertensive Agents
Homeostasis
Obesity
Cross-Sectional Studies
Insulin
Hypertension
Serum

Keywords

  • Antihypertensive treatment
  • Blood pressure control
  • Obesity

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Relation between blood pressure control, body mass index, and intensity of medical treatment. / Saito, Ikuo; Murata, Kazuko; Hirose, Hiroshi; Tsujioka, Minako; Kawabe, Hiroshi.

In: Hypertension Research, Vol. 26, No. 9, 01.09.2003, p. 711-715.

Research output: Contribution to journalArticle

Saito, Ikuo ; Murata, Kazuko ; Hirose, Hiroshi ; Tsujioka, Minako ; Kawabe, Hiroshi. / Relation between blood pressure control, body mass index, and intensity of medical treatment. In: Hypertension Research. 2003 ; Vol. 26, No. 9. pp. 711-715.
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