Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese

24-year follow-up of NIPPON DATA80

for the NIPPON DATA80 Research Group

Research output: Contribution to journalArticle

Abstract

Background/Objectives: The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population. Subjects/Methods: We prospectively followed 8925 participants (3916 men and 5009 women) aged 30–79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs) for CVD mortality by quartiles of exposure variables. Results: During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95% CI: 0.47–0.87; P trend = 0.007) compared with the lowest quartile. This association was not significant in women. Multivariable-adjusted HR for total stroke mortality was lower in the highest quartile of DF intake (HR: 0.61, 95% CI: 0.38–0.98) compared with the lowest quartile in women. Carbohydrate, available carbohydrate, and starch intake were not associated with CVD mortality. Conclusions: Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women.

Original languageEnglish
JournalEuropean Journal of Clinical Nutrition
DOIs
Publication statusPublished - 2019 Jan 1

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Dietary Fiber
Cardiovascular Diseases
Carbohydrates
Mortality
Starch
Confidence Intervals
Stroke
Dietary Carbohydrates
Nutrition Surveys
Proportional Hazards Models
Japan

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

@article{5abdeafa5c714fa0ab0d9f7330eccbfd,
title = "Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese: 24-year follow-up of NIPPON DATA80",
abstract = "Background/Objectives: The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population. Subjects/Methods: We prospectively followed 8925 participants (3916 men and 5009 women) aged 30–79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95{\%} confidence intervals (CIs) for CVD mortality by quartiles of exposure variables. Results: During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95{\%} CI: 0.47–0.87; P trend = 0.007) compared with the lowest quartile. This association was not significant in women. Multivariable-adjusted HR for total stroke mortality was lower in the highest quartile of DF intake (HR: 0.61, 95{\%} CI: 0.38–0.98) compared with the lowest quartile in women. Carbohydrate, available carbohydrate, and starch intake were not associated with CVD mortality. Conclusions: Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women.",
author = "{for the NIPPON DATA80 Research Group} and Itsuko Miyazawa and Katsuyuki Miura and Naoko Miyagawa and Keiko Kondo and Aya Kadota and Nagako Okuda and Akira Fujiyoshi and Izumi Chihara and Yosikazu Nakamura and Atsushi Hozawa and Yasuyuki Nakamura and Yoshikuni Kita and Katsushi Yoshita and Tomonori Okamura and Akira Okayama and Hirotsugu Ueshima",
year = "2019",
month = "1",
day = "1",
doi = "10.1038/s41430-019-0424-y",
language = "English",
journal = "European Journal of Clinical Nutrition",
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TY - JOUR

T1 - Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese

T2 - 24-year follow-up of NIPPON DATA80

AU - for the NIPPON DATA80 Research Group

AU - Miyazawa, Itsuko

AU - Miura, Katsuyuki

AU - Miyagawa, Naoko

AU - Kondo, Keiko

AU - Kadota, Aya

AU - Okuda, Nagako

AU - Fujiyoshi, Akira

AU - Chihara, Izumi

AU - Nakamura, Yosikazu

AU - Hozawa, Atsushi

AU - Nakamura, Yasuyuki

AU - Kita, Yoshikuni

AU - Yoshita, Katsushi

AU - Okamura, Tomonori

AU - Okayama, Akira

AU - Ueshima, Hirotsugu

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background/Objectives: The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population. Subjects/Methods: We prospectively followed 8925 participants (3916 men and 5009 women) aged 30–79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs) for CVD mortality by quartiles of exposure variables. Results: During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95% CI: 0.47–0.87; P trend = 0.007) compared with the lowest quartile. This association was not significant in women. Multivariable-adjusted HR for total stroke mortality was lower in the highest quartile of DF intake (HR: 0.61, 95% CI: 0.38–0.98) compared with the lowest quartile in women. Carbohydrate, available carbohydrate, and starch intake were not associated with CVD mortality. Conclusions: Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women.

AB - Background/Objectives: The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population. Subjects/Methods: We prospectively followed 8925 participants (3916 men and 5009 women) aged 30–79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs) for CVD mortality by quartiles of exposure variables. Results: During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95% CI: 0.47–0.87; P trend = 0.007) compared with the lowest quartile. This association was not significant in women. Multivariable-adjusted HR for total stroke mortality was lower in the highest quartile of DF intake (HR: 0.61, 95% CI: 0.38–0.98) compared with the lowest quartile in women. Carbohydrate, available carbohydrate, and starch intake were not associated with CVD mortality. Conclusions: Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women.

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U2 - 10.1038/s41430-019-0424-y

DO - 10.1038/s41430-019-0424-y

M3 - Article

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

SN - 0954-3007

ER -