Relationship between characteristics of genetic study and essential thrombocythemia in aged patients

Toshihide Harada, Fumiko Ishizaki, Yumiko Miki, Yumiko Nitta, Miwa Hayama, Jyunnya Aonaka, Yuko Kodama, Shoji Ito, Ryuta Yamamoto, Katsuyuki Niyada, Hiroyuki Miyazaki, Satomi Aoi, Hiromi Ikeda, Tadayuki Iida, Hanayo Hiroto, Juko Ando, Kohsaku Nitta

Research output: Contribution to journalArticle

Abstract

Objective: Essential thrombocythaemia is a rare disease. Design: A clinical study. Materials and Methods: An 86-year-old man had marked thrombocytosis, increased leukocyte count and anemia. Analysis of the Janus Activating Kinase 2 (JAK2) V617F (GTC→TTC) gene from his leukocytes demonstrated the JAK2 mutation (V617F GTC→TTC, G1849T, exon 14). Results: A diagnosis of essential Thrombocythaemia was made. Conclusions: He has been good in health without chemotherapy since then.

Original languageEnglish
Pages (from-to)438-439
Number of pages2
JournalInternational Medical Journal
Volume26
Issue number5
Publication statusPublished - 2019 Jan 1

Fingerprint

Janus Kinase 2
Essential Thrombocythemia
Thrombocytosis
Rare Diseases
Leukocyte Count
Anemia
Exons
Leukocytes
Drug Therapy
Mutation
Health
Genes
Clinical Studies

Keywords

  • Aged patient
  • Essential thrombocythaemia
  • JAK2 mutation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Harada, T., Ishizaki, F., Miki, Y., Nitta, Y., Hayama, M., Aonaka, J., ... Nitta, K. (2019). Relationship between characteristics of genetic study and essential thrombocythemia in aged patients. International Medical Journal, 26(5), 438-439.

Relationship between characteristics of genetic study and essential thrombocythemia in aged patients. / Harada, Toshihide; Ishizaki, Fumiko; Miki, Yumiko; Nitta, Yumiko; Hayama, Miwa; Aonaka, Jyunnya; Kodama, Yuko; Ito, Shoji; Yamamoto, Ryuta; Niyada, Katsuyuki; Miyazaki, Hiroyuki; Aoi, Satomi; Ikeda, Hiromi; Iida, Tadayuki; Hiroto, Hanayo; Ando, Juko; Nitta, Kohsaku.

In: International Medical Journal, Vol. 26, No. 5, 01.01.2019, p. 438-439.

Research output: Contribution to journalArticle

Harada, T, Ishizaki, F, Miki, Y, Nitta, Y, Hayama, M, Aonaka, J, Kodama, Y, Ito, S, Yamamoto, R, Niyada, K, Miyazaki, H, Aoi, S, Ikeda, H, Iida, T, Hiroto, H, Ando, J & Nitta, K 2019, 'Relationship between characteristics of genetic study and essential thrombocythemia in aged patients', International Medical Journal, vol. 26, no. 5, pp. 438-439.
Harada T, Ishizaki F, Miki Y, Nitta Y, Hayama M, Aonaka J et al. Relationship between characteristics of genetic study and essential thrombocythemia in aged patients. International Medical Journal. 2019 Jan 1;26(5):438-439.
Harada, Toshihide ; Ishizaki, Fumiko ; Miki, Yumiko ; Nitta, Yumiko ; Hayama, Miwa ; Aonaka, Jyunnya ; Kodama, Yuko ; Ito, Shoji ; Yamamoto, Ryuta ; Niyada, Katsuyuki ; Miyazaki, Hiroyuki ; Aoi, Satomi ; Ikeda, Hiromi ; Iida, Tadayuki ; Hiroto, Hanayo ; Ando, Juko ; Nitta, Kohsaku. / Relationship between characteristics of genetic study and essential thrombocythemia in aged patients. In: International Medical Journal. 2019 ; Vol. 26, No. 5. pp. 438-439.
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