Relationship between event-related desynchronization and cortical excitability in healthy subjects and stroke patients

Koji Aono, Shotaro Miyashita, Yosuke Fujiwara, Mitsuhiko Kodama, Kozo Hanayama, Yoshihisa Masakado, Junichi Ushiba

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective: Relation between cortical excitability and magnitudes of event-related dysynchronizaton (ERD) has not been clarified. This study was investigated that relationshp between cortical excitability and ERD magnitudes in healthy subjects and stroke patients. Methods: Ten healthy subjects and four patients with stroke participated in this study. EEGs were recorded over the sensorimotor cortex (left hemisphere in healthy subjects; damaged hemisphere in stroke subjects) to calculate ERD during motor imagery,. Motor-evoked potential (MEP) induced by single-pulse transcranial magnetic stimulation over the primary motor cortex was recorded from the first dorsal interosseus (FDI) muscle at ERD magnitudes of 10% and 30%. Results: MEP significantly increased at 10% and 30% ERD (p < 0.01) than that during rest in healthy subjects. The 30% ERD condition showed significantly higher MEP than that at 10% ERD (p < 0.05). In stroke patients, MEP increased with ERD induced by motor imagery, but the change of MEP to ERD amplitude was critically different among the subject. Conclusion: ERD magnitude corresponds to corticospinal excitability increases in healthy subjects and patients with hemiplegic stroke. BCI based on motor imagery-induced ERD may be a potential rehabilitation strategy for patients with hemiplegic stroke.

Original languageEnglish
Pages (from-to)123-128
Number of pages6
JournalTokai Journal of Experimental and Clinical Medicine
Volume38
Issue number4
Publication statusPublished - 2013

Fingerprint

Motor Evoked Potentials
Healthy Volunteers
Stroke
Imagery (Psychotherapy)
Transcranial Magnetic Stimulation
Motor Cortex
Cortical Excitability
Electroencephalography
Rehabilitation
Muscles

Keywords

  • Corticospinal excitability
  • Event-related desynchronization
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Relationship between event-related desynchronization and cortical excitability in healthy subjects and stroke patients. / Aono, Koji; Miyashita, Shotaro; Fujiwara, Yosuke; Kodama, Mitsuhiko; Hanayama, Kozo; Masakado, Yoshihisa; Ushiba, Junichi.

In: Tokai Journal of Experimental and Clinical Medicine, Vol. 38, No. 4, 2013, p. 123-128.

Research output: Contribution to journalArticle

Aono, Koji ; Miyashita, Shotaro ; Fujiwara, Yosuke ; Kodama, Mitsuhiko ; Hanayama, Kozo ; Masakado, Yoshihisa ; Ushiba, Junichi. / Relationship between event-related desynchronization and cortical excitability in healthy subjects and stroke patients. In: Tokai Journal of Experimental and Clinical Medicine. 2013 ; Vol. 38, No. 4. pp. 123-128.
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