Relative and absolute stereochemistry of the melanogenesis inhibitors OH-3984 K1 and K2. Partial synthesis from albocycline

Toshiaki Sunazuka; Rika Obata; Li Zhuorong; Satoshi Takamatsu; Kanki Komiyama; Satoshi Omura; Amos B. Smith

doi:10.1016/S0040-4039(00)76992-9

Relative and absolute stereochemistry of the melanogenesis inhibitors OH-3984 K1 and K2. Partial synthesis from albocycline

Toshiaki Sunazuka, Rika Obata, Li Zhuorong, Satoshi Takamatsu, Kanki Komiyama, Satoshi Omura, Amos B. Smith

Department of Humanities and Social Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The transformation of the macrolide antibiotic albocycline (3) to the recently isolated melanin synthesis inhibitors OH-3984 K1 (1 and K2 (2) has established the relative and absolute configurations of 1 (4R, 7R, 12S) and 2 (4R, 7R, 12S, 13R).

Original language	English
Pages (from-to)	2635-2636
Number of pages	2
Journal	Tetrahedron Letters
Volume	35
Issue number	17
DOIs	https://doi.org/10.1016/S0040-4039(00)76992-9
Publication status	Published - 1994 Apr 25

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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Relative and absolute stereochemistry of the melanogenesis inhibitors OH-3984 K1 and K2. Partial synthesis from albocycline. / Sunazuka, Toshiaki; Obata, Rika; Zhuorong, Li; Takamatsu, Satoshi; Komiyama, Kanki; Omura, Satoshi; Smith, Amos B.

In: Tetrahedron Letters, Vol. 35, No. 17, 25.04.1994, p. 2635-2636.

Research output: Contribution to journal › Article › peer-review

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AU - Sunazuka, Toshiaki

AU - Obata, Rika

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AU - Takamatsu, Satoshi

AU - Komiyama, Kanki

AU - Omura, Satoshi

AU - Smith, Amos B.

PY - 1994/4/25

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AB - The transformation of the macrolide antibiotic albocycline (3) to the recently isolated melanin synthesis inhibitors OH-3984 K1 (1 and K2 (2) has established the relative and absolute configurations of 1 (4R, 7R, 12S) and 2 (4R, 7R, 12S, 13R).

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SN - 0040-4039

IS - 17

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Relative and absolute stereochemistry of the melanogenesis inhibitors OH-3984 K1 and K2. Partial synthesis from albocycline

Abstract

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