Relative and absolute stereochemistry of the melanogenesis inhibitors OH-3984 K1 and K2. Partial synthesis from albocycline

Toshiaki Sunazuka, Rika Obata, Li Zhuorong, Satoshi Takamatsu, Kanki Komiyama, Satoshi Omura, Amos B. Smith

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The transformation of the macrolide antibiotic albocycline (3) to the recently isolated melanin synthesis inhibitors OH-3984 K1 (1 and K2 (2) has established the relative and absolute configurations of 1 (4R, 7R, 12S) and 2 (4R, 7R, 12S, 13R).

Original languageEnglish
Pages (from-to)2635-2636
Number of pages2
JournalTetrahedron Letters
Volume35
Issue number17
DOIs
Publication statusPublished - 1994 Apr 25

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Relative and absolute stereochemistry of the melanogenesis inhibitors OH-3984 K1 and K2. Partial synthesis from albocycline'. Together they form a unique fingerprint.

Cite this