Abstract
We investigated the photovasorelaxation with intravascular transluminal irradiation using in vivo model. A 2.5 Fr. catheter was inserted in the femoral artery of a rabbit under anesthesia. A 400 μ m diameter quartz fiber was inserted through the catheter. The catheter was withdrawn from the distal end to the proximal end of the exposed femoral artery without laser irradiation in order to observe the mechanical dilation by the procedure. The femoral artery lumen was inadiated by a Helium-Cadmium(He-Cd) laser (wave length; 325 nm) with 8 mW through the fiber during 30 s. We carried out that the laser irradiation produced vasorelaxation (185% on the average) compared with mechanical vasodilation (150% on the average) with angiography. The results suggest that intravascular transluminal irradiation with low-power UV laser might be applicable to the relief of acute arterial vasospasm.
| Original language | English |
|---|---|
| Pages (from-to) | 42-45 |
| Number of pages | 4 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 3254 |
| DOIs | |
| Publication status | Published - 1998 Dec 1 |
| Event | Laser-Tissue Interaction IX - San Jose, CA, United States Duration: 1998 Jan 26 → 1998 Jan 28 |
Keywords
- Femoral artery
- Helium-Cadmium laser
- Laser irradiation
- Nitric oxide
- Photorelaxation
- Rabbit
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering