Removal of sodium ion from bile acid solution using diffusional dialysis with cation exchange membrane

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3 Citations (Scopus)

Abstract

The behavior of sodium ions passing through a CM1 cation exchange membrane was studied with electroconductive and diffusional membrane permeabilities based on nonequilibrium thermodynamics to remove sodium ion from bile acid solution. These membrane permeabilities of sodium ion in order of amplitude showed sodium chloride > sodiumtaurocholate > sodium cholate systems in all cases. In the sodium cholate and sodium taurocholate systems, the curves relating the electroconductive membrane permeability with concentration showed distinct changes in gradient at around the concentration of primary micelle formation of each bile acid solution. This was attributable to an increase in membrane/solution distribution of bile acid anion on basis of the micelle formation. Using diffusional dialysis, 7.3% of sodium ion was removed from rat serum. Sodium ion was significantly reduced with increasing total bile acid concentration in rat serum (P <0.05; correlation coefficient=-0.606).

Original languageEnglish
Pages (from-to)189-197
Number of pages9
JournalSeparation and Purification Technology
Volume33
Issue number2
DOIs
Publication statusPublished - 2003 Oct 1
Externally publishedYes

Fingerprint

Dialysis
Bile Acids and Salts
Cations
Ion exchange
Positive ions
Sodium
Ions
Membranes
Acids
Sodium Cholate
Micelles
Rats
Taurocholic Acid
Sodium Chloride
Anions
Thermodynamics
Sodium chloride
Negative ions

Keywords

  • Cation exchange membrane
  • Cholate
  • Membrane permeability
  • Rat serum
  • Sodium
  • Taurocholate

ASJC Scopus subject areas

  • Filtration and Separation

Cite this

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abstract = "The behavior of sodium ions passing through a CM1 cation exchange membrane was studied with electroconductive and diffusional membrane permeabilities based on nonequilibrium thermodynamics to remove sodium ion from bile acid solution. These membrane permeabilities of sodium ion in order of amplitude showed sodium chloride > sodiumtaurocholate > sodium cholate systems in all cases. In the sodium cholate and sodium taurocholate systems, the curves relating the electroconductive membrane permeability with concentration showed distinct changes in gradient at around the concentration of primary micelle formation of each bile acid solution. This was attributable to an increase in membrane/solution distribution of bile acid anion on basis of the micelle formation. Using diffusional dialysis, 7.3{\%} of sodium ion was removed from rat serum. Sodium ion was significantly reduced with increasing total bile acid concentration in rat serum (P <0.05; correlation coefficient=-0.606).",
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AB - The behavior of sodium ions passing through a CM1 cation exchange membrane was studied with electroconductive and diffusional membrane permeabilities based on nonequilibrium thermodynamics to remove sodium ion from bile acid solution. These membrane permeabilities of sodium ion in order of amplitude showed sodium chloride > sodiumtaurocholate > sodium cholate systems in all cases. In the sodium cholate and sodium taurocholate systems, the curves relating the electroconductive membrane permeability with concentration showed distinct changes in gradient at around the concentration of primary micelle formation of each bile acid solution. This was attributable to an increase in membrane/solution distribution of bile acid anion on basis of the micelle formation. Using diffusional dialysis, 7.3% of sodium ion was removed from rat serum. Sodium ion was significantly reduced with increasing total bile acid concentration in rat serum (P <0.05; correlation coefficient=-0.606).

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