Renal angiomyolipoma: A radiological classification and update on recent developments in diagnosis and management

Masahiro Jinzaki, Stuart G. Silverman, Hirotaka Akita, Yoji Nagashima, Shuji Mikami, Mototsugu Oya

Research output: Contribution to journalArticle

127 Citations (Scopus)

Abstract

Angiomyolipoma is the most common benign solid renal neoplasm observed in clinical practice. Once thought to be a hamartoma and almost always diagnosed by the imaged-based detection of fat, angiomyolipomas are now known to consist of a heterogeneous group of neoplasms. Although all are considered perivascular epithelioid cell tumors, many display different pathology, imaging features, and clinical behavior. The importance of understanding this group of neoplasms is emphasized by the fact that many types of angiomyolipoma contain little to no fat, and despite being benign, sometimes escape a pre-operative diagnosis. These types of angiomyolipomas can all be considered when encountering a renal mass that is both hyperattenuating relative to renal parenchyma on unenhanced CT and T2-hypointense, features that reflect their predominant smooth muscle component. We review recent developments and provide a radiological classification of angiomyolipomas that helps physicians understand the various types and learn how to both diagnose and manage them.

Original languageEnglish
Pages (from-to)588-604
Number of pages17
JournalAbdominal Imaging
Volume39
Issue number3
DOIs
Publication statusPublished - 2014 Jun

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Keywords

  • AML with minimal fat
  • Angiomyolipoma
  • Fat poor AML
  • PEComa
  • Perivascular epithelioid cell tumors
  • Renal cell carcinoma

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

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