Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

Takeshi Fukawa, Koji Takematsu, Kotaro Oka, Nobuyuki Miyahara, Sachiko Koike, Koichi Ando, Hirosuke Kobayashi, Kazuo Tanishita

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

We measured directly the partial pressure of oxygen (pO2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O2 electrodes in vivo. The pO2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Pages371-372
Number of pages2
Volume39
Publication statusPublished - 1998

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Tumors
Irradiation
Tissue
X rays
Carbon
Partial pressure
Dosimetry
Electrodes
Oxygen

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Fukawa, T., Takematsu, K., Oka, K., Miyahara, N., Koike, S., Ando, K., ... Tanishita, K. (1998). Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 39, pp. 371-372)

Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation. / Fukawa, Takeshi; Takematsu, Koji; Oka, Kotaro; Miyahara, Nobuyuki; Koike, Sachiko; Ando, Koichi; Kobayashi, Hirosuke; Tanishita, Kazuo.

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 39 1998. p. 371-372.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fukawa, T, Takematsu, K, Oka, K, Miyahara, N, Koike, S, Ando, K, Kobayashi, H & Tanishita, K 1998, Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation. in American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. vol. 39, pp. 371-372.
Fukawa T, Takematsu K, Oka K, Miyahara N, Koike S, Ando K et al. Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 39. 1998. p. 371-372
Fukawa, Takeshi ; Takematsu, Koji ; Oka, Kotaro ; Miyahara, Nobuyuki ; Koike, Sachiko ; Ando, Koichi ; Kobayashi, Hirosuke ; Tanishita, Kazuo. / Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 39 1998. pp. 371-372
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AU - Fukawa, Takeshi

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AU - Oka, Kotaro

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AU - Koike, Sachiko

AU - Ando, Koichi

AU - Kobayashi, Hirosuke

AU - Tanishita, Kazuo

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