Abstract
In Crohn's disease, characterized by longitudinal ulcers and a cobblestone appearance of the intestinal mucosa, massive lower intestinal bleeding requiring blood transfusions to maintain normal vital signs is a relatively rare complication (1-3% of all cases). Although surgery may be the most appropriate treatment for such massive bleeding, recurrent hemorrhage is occasionally encountered. We describe a 23-year-old male patient with Crohn's disease who suffered massive bleeding three times within a two-year period, and successful hemostasis was obtained by endoscopic local injection of hypertonic saline epinephrine (HSE) and clipping on each occasion. It is rare for episodes of massive lower intestinal bleeding in Crohn's disease to be repeated over a relatively short period. In the present patient, emergency colonoscopy was diagnostically helpful, and the bleeding was successfully controlled by endoscopic therapy. Thus, endoscopic therapy should be used conservatively in Crohn's disease with recurrent major hemorrhage to avoid multiple abdominal surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 2087-2094 |
| Number of pages | 8 |
| Journal | Gastroenterological Endoscopy |
| Volume | 44 |
| Issue number | 12 |
| Publication status | Published - 2002 Dec 1 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Gastroenterology
Cite this
Repeated massive lower intestinal bleeding in Crohn's disease : Successful control by endoscopic therapy. / Tsubouchi, Yuh; Kouyama, Harukazu; Kawanishi, Teruaki; Nishimori, Hiroyuki; Goto, Kenichirou; Mima, Satoaki; Takasugi, Hiderou; Imai, Kiichi; Iwao, Yasushi; Hibi, Toshifumi.
In: Gastroenterological Endoscopy, Vol. 44, No. 12, 01.12.2002, p. 2087-2094.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Repeated massive lower intestinal bleeding in Crohn's disease
T2 - Successful control by endoscopic therapy
AU - Tsubouchi, Yuh
AU - Kouyama, Harukazu
AU - Kawanishi, Teruaki
AU - Nishimori, Hiroyuki
AU - Goto, Kenichirou
AU - Mima, Satoaki
AU - Takasugi, Hiderou
AU - Imai, Kiichi
AU - Iwao, Yasushi
AU - Hibi, Toshifumi
PY - 2002/12/1
Y1 - 2002/12/1
N2 - In Crohn's disease, characterized by longitudinal ulcers and a cobblestone appearance of the intestinal mucosa, massive lower intestinal bleeding requiring blood transfusions to maintain normal vital signs is a relatively rare complication (1-3% of all cases). Although surgery may be the most appropriate treatment for such massive bleeding, recurrent hemorrhage is occasionally encountered. We describe a 23-year-old male patient with Crohn's disease who suffered massive bleeding three times within a two-year period, and successful hemostasis was obtained by endoscopic local injection of hypertonic saline epinephrine (HSE) and clipping on each occasion. It is rare for episodes of massive lower intestinal bleeding in Crohn's disease to be repeated over a relatively short period. In the present patient, emergency colonoscopy was diagnostically helpful, and the bleeding was successfully controlled by endoscopic therapy. Thus, endoscopic therapy should be used conservatively in Crohn's disease with recurrent major hemorrhage to avoid multiple abdominal surgery.
AB - In Crohn's disease, characterized by longitudinal ulcers and a cobblestone appearance of the intestinal mucosa, massive lower intestinal bleeding requiring blood transfusions to maintain normal vital signs is a relatively rare complication (1-3% of all cases). Although surgery may be the most appropriate treatment for such massive bleeding, recurrent hemorrhage is occasionally encountered. We describe a 23-year-old male patient with Crohn's disease who suffered massive bleeding three times within a two-year period, and successful hemostasis was obtained by endoscopic local injection of hypertonic saline epinephrine (HSE) and clipping on each occasion. It is rare for episodes of massive lower intestinal bleeding in Crohn's disease to be repeated over a relatively short period. In the present patient, emergency colonoscopy was diagnostically helpful, and the bleeding was successfully controlled by endoscopic therapy. Thus, endoscopic therapy should be used conservatively in Crohn's disease with recurrent major hemorrhage to avoid multiple abdominal surgery.
UR - http://www.scopus.com/inward/record.url?scp=0036947930&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036947930&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0036947930
VL - 44
SP - 2087
EP - 2094
JO - Gastroenterological Endoscopy
JF - Gastroenterological Endoscopy
SN - 0387-1207
IS - 12
ER -