TY - JOUR
T1 - Repeated regression of pulmonary metastases from renal cell carcinoma after treatment using different interferon-alpha preparations
AU - Oya, Mototsugu
AU - Asakura, Hirotaka
AU - Mizuno, Ryuichi
AU - Marumo, Ken
AU - Murai, Masaru
PY - 2005/6
Y1 - 2005/6
N2 - A 49-year-old man with pulmonary metastasis from renal cell carcinoma (RCC) was treated with recombinant IFN-α2b (Intron A®). A complete response was achieved within 4 months and thereafter persisted for 5 years until he developed another lung lesion. Interleukin-2 (Imunace®) was administered without any response. Finally, lie was treated by natural IFN-α (OIF®). The pulmonary lesion achieved a partial response after 11 months of treatment. Because IFN-α preparations include different subtypes, changing the use of IFN-α preparations may thus be a potentially useful option for the successful immunotherapy of RCC.
AB - A 49-year-old man with pulmonary metastasis from renal cell carcinoma (RCC) was treated with recombinant IFN-α2b (Intron A®). A complete response was achieved within 4 months and thereafter persisted for 5 years until he developed another lung lesion. Interleukin-2 (Imunace®) was administered without any response. Finally, lie was treated by natural IFN-α (OIF®). The pulmonary lesion achieved a partial response after 11 months of treatment. Because IFN-α preparations include different subtypes, changing the use of IFN-α preparations may thus be a potentially useful option for the successful immunotherapy of RCC.
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U2 - 10.2220/biomedres.26.135
DO - 10.2220/biomedres.26.135
M3 - Article
C2 - 16011307
AN - SCOPUS:27244461045
VL - 26
SP - 135
EP - 137
JO - Biomedical Research (Japan)
JF - Biomedical Research (Japan)
SN - 0388-6107
IS - 3
ER -