Replacement therapy of adrenal insufficiency

Ayuko Suzuki, Tomonobu Hasegawa

Research output: Contribution to journalArticle

Abstract

The adrenal cortex produces three principal categories of steroid hormones that regulate a wide variety of physiologic process from fetal to adult. Three steroid hormones are glucocorticoids (principally cortisol), mineralocorticoids (principally aldosterone) and adrenal androgens. Glucocorticoids are named for their carbohydrate mobilizing activity but are ubiquitous physiologic regulators influencing a wide variety of bodily functions. In case of deficiency of endogenous adrenal cortex steroid hormones, glucocorticoid replacement therapy is employed. There are two pathologic forms in steroid hormones deficiency, one is "the primary" that is adrenal failure and the other is "the secondary" that is pituitary failure. Symptoms and treatments are different between the two forms and onset (acute or chronic).

Original languageEnglish
Pages (from-to)157-162
Number of pages6
JournalNippon rinsho. Japanese journal of clinical medicine
Volume66
Issue number1
Publication statusPublished - 2008 Jan

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Adrenal Insufficiency
Steroids
Glucocorticoids
Hormones
Mineralocorticoids
Adrenal Cortex
Hormone Replacement Therapy
Therapeutics
Aldosterone
Androgens
Hydrocortisone
Adrenal Cortex Hormones
Carbohydrates

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Replacement therapy of adrenal insufficiency. / Suzuki, Ayuko; Hasegawa, Tomonobu.

In: Nippon rinsho. Japanese journal of clinical medicine, Vol. 66, No. 1, 01.2008, p. 157-162.

Research output: Contribution to journalArticle

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