Repression of an ascidian gene in the tip of the tail of tail-bud-stage embryos

Kohji Hotta, Hiroki Takahashi, Noriyuki Satoh

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


The occurrence of tadpole-type larvae is one of the key events used to understand the origin and evolution of chordates, and the rail bud of chordate embryos is thought to be associated with formation of the tip of the tail. Although some transcriptional factor genes including Brachyury are expressed in the tail bud, no structural genes have been reported to be expressed there. We report here that an ascidian gene HrTT-1 is expressed exclusively in the tip of elongating tail of the tail-bud embryo. This gene encodes a possible secreted protein of 415 amino acids with the SCP/TPX family consensus sequences.

Original languageEnglish
Pages (from-to)164-167
Number of pages4
JournalDevelopment Genes and Evolution
Issue number3
Publication statusPublished - 1998
Externally publishedYes


  • Ascidians
  • SCP/TPX family sequences
  • Specific genes
  • Tail bud
  • Tip of the tail

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology


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