Reproducibility of Growth Hormone Stimulation Tests (Arginine and Insulin), Insulin-Like Growth Factor (Igf)-I and Igf-Binding Protein-3 Measurements

Yukihiro Hasegawa, Tomonobu Hasegawa, Shinobu Kotoh, Yutaka Tsuchiya

Research output: Contribution to journalArticle

4 Citations (Scopus)


Recently there have been some data suggesting that the results of GH stimulation tests are not reproducible. We studied here the reproducibility of GH stimulation tests (arginine and insulin) and compared it with the reproducibility of serum IGF-I and IGFBP-3 measurements. the interdaily variation of traditional GH tests can be higher than that of IGF-I and IGFBP-3 measurements. We should not over-rely upon traditional GH stimulation tests to diagnose GH insufficiency.

Original languageEnglish
Pages (from-to)75-78
Number of pages4
JournalClinical Pediatric Endocrinology
Issue number1
Publication statusPublished - 1993
Externally publishedYes



  • arginine
  • GH stimulation tests
  • IGF-I
  • IGFBP-3
  • insulin tests
  • reproducibility

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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