@article{a0a496ec993a4d07a5ab1e80fd869d06,
title = " Response to Fungal Dysbiosis by Gut-Resident CX3CR1 + Mononuclear Phagocytes Aggravates Allergic Airway Disease ",
abstract = "How mycobiota influence immunity in gut distal sites is not well understood. Li et al. developed protocols for gut-targeted depletion of phagocytes and mycobiota-free mice to investigate the influence of fungi on gut-lung crosstalk. They reveal that intestinal phagocytes sense fungal dysbiosis and mediate gut-lung-directed immunity to aggravate allergic airway disease.",
keywords = "CX3CR1 mononuclear phagocytes, fungi, gut-lung axis, mycobiome, mycobiota dysbiosis",
author = "Xin Li and Irina Leonardi and Alexa Semon and Itai Doron and Gao, {Iris H.} and Putzel, {Gregory Garb{\`e}s} and Youngjun Kim and Hiroki Kabata and David Artis and Fiers, {William D.} and Ramer-Tait, {Amanda E.} and Iliev, {Iliyan D.}",
note = "Funding Information: This work was funded by the US National Institutes of Health (grants DK113136 and AI137157 to I.D.I.), Kenneth Rainin Foundation , Irma T. Hirschl Career Scientist award to I.D.I., and support from the Jill Roberts Institute for Research in Inflammatory Bowel Disease . We thank Dr. J. David Warren for assistance with the LC-MS/MS. Funding Information: This work was funded by the US National Institutes of Health (grants DK113136 and AI137157 to I.D.I.), Kenneth Rainin Foundation, Irma T. Hirschl Career Scientist award to I.D.I., and support from the Jill Roberts Institute for Research in Inflammatory Bowel Disease. We thank Dr. J. David Warren for assistance with the LC-MS/MS. Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",
year = "2018",
month = dec,
day = "12",
doi = "10.1016/j.chom.2018.11.003",
language = "English",
volume = "24",
pages = "847--856.e4",
journal = "Cell Host and Microbe",
issn = "1931-3128",
publisher = "Cell Press",
number = "6",
}