Reticuloendothelial system-potentiating and alkaline phosphatase-inducing activities of plantago-mucilage A, the main mucilage from the seed of Plantago asiatica, and its five modification products

M. Tomoda, K. Takada, N. Shimizu, Ryoko Gonda, N. Ohara

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10 Citations (Scopus)

Abstract

Five kinds of chemically modified products were prepared from Plantago-mucilage A, the representative mucous polysaccharide isolated from the seed of Plantago asiatica L., and their reticuloendothelial system-potentiating and alkaline phosphatase-inducing activities have been investigated. Both activities were markedly enhanced when the mucilage was de-O-acetylated. The products obtained by periodate oxidation, controlled Smith degradation, and partial acid hydrolysis under the two conditions were not effective. Structural features of the partial hydrolyzates were elucidated, and it was shown that these products lost all O-acetyl groups, all xylose branches and many hexuronosyl arabinose side chains.

Original languageEnglish
Pages (from-to)2068-2071
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume39
Issue number8
Publication statusPublished - 1991

Fingerprint

Psyllium
Plantago
Mononuclear Phagocyte System
Arabinose
Xylose
Polysaccharides
Alkaline Phosphatase
Hydrolysis
Degradation
Oxidation
Acids
metaperiodate

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

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abstract = "Five kinds of chemically modified products were prepared from Plantago-mucilage A, the representative mucous polysaccharide isolated from the seed of Plantago asiatica L., and their reticuloendothelial system-potentiating and alkaline phosphatase-inducing activities have been investigated. Both activities were markedly enhanced when the mucilage was de-O-acetylated. The products obtained by periodate oxidation, controlled Smith degradation, and partial acid hydrolysis under the two conditions were not effective. Structural features of the partial hydrolyzates were elucidated, and it was shown that these products lost all O-acetyl groups, all xylose branches and many hexuronosyl arabinose side chains.",
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T1 - Reticuloendothelial system-potentiating and alkaline phosphatase-inducing activities of plantago-mucilage A, the main mucilage from the seed of Plantago asiatica, and its five modification products

AU - Tomoda, M.

AU - Takada, K.

AU - Shimizu, N.

AU - Gonda, Ryoko

AU - Ohara, N.

PY - 1991

Y1 - 1991

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AB - Five kinds of chemically modified products were prepared from Plantago-mucilage A, the representative mucous polysaccharide isolated from the seed of Plantago asiatica L., and their reticuloendothelial system-potentiating and alkaline phosphatase-inducing activities have been investigated. Both activities were markedly enhanced when the mucilage was de-O-acetylated. The products obtained by periodate oxidation, controlled Smith degradation, and partial acid hydrolysis under the two conditions were not effective. Structural features of the partial hydrolyzates were elucidated, and it was shown that these products lost all O-acetyl groups, all xylose branches and many hexuronosyl arabinose side chains.

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