Abstract
Background/Aim:We developed a novel visuospatial clinical task to detect parietal dysfunction in mild Alzheimers disease (AD). Methods: A total of 65 outpatients, including 47 with mild AD and 18 cognitively and neuroradiologically normal individuals with subjective memory impairment (NL), performed the Reverse Fox test and underwent brain single photon emission tomography. Patients with AD were divided into subgroups according to the results of the Reverse Fox test (successful vs unsuccessful). Results: Success in the Reverse Fox test was achieved by 31.9% of patients with AD and 94.4% of NL. The unsuccessful AD subgroup had reduced perfusion of the medial parietal and bilateral temporoparietal regions compared with the successful AD subgroup. Conclusions: Failure in the Reverse Fox test was related to parietal hypoperfusion in patients with mild AD. Our findings suggest that the Reverse Fox test may be one of the useful supporting tools for detecting mild AD at outpatient clinic.
| Original language | English |
|---|---|
| Pages (from-to) | 177-182 |
| Number of pages | 6 |
| Journal | American Journal of Alzheimer's Disease and other Dementias |
| Volume | 29 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- Alzheimer's disease
- gesture imitation
- screening test
- single photon emission computed tomography
- visuospatial abilities
ASJC Scopus subject areas
- Psychiatry and Mental health
- Geriatrics and Gerontology
- Clinical Psychology
- Medicine(all)
Cite this
Reverse fox test for detecting visuospatial dysfunction corresponding to parietal hypoperfusion in mild alzheimer's disease. / Tabuchi, Hajime; Konishi, Mika; Saito, Nao; Kato, Motoichiro; Mimura, Masaru.
In: American Journal of Alzheimer's Disease and other Dementias, Vol. 29, No. 2, 2014, p. 177-182.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reverse fox test for detecting visuospatial dysfunction corresponding to parietal hypoperfusion in mild alzheimer's disease
AU - Tabuchi, Hajime
AU - Konishi, Mika
AU - Saito, Nao
AU - Kato, Motoichiro
AU - Mimura, Masaru
PY - 2014
Y1 - 2014
N2 - Background/Aim:We developed a novel visuospatial clinical task to detect parietal dysfunction in mild Alzheimers disease (AD). Methods: A total of 65 outpatients, including 47 with mild AD and 18 cognitively and neuroradiologically normal individuals with subjective memory impairment (NL), performed the Reverse Fox test and underwent brain single photon emission tomography. Patients with AD were divided into subgroups according to the results of the Reverse Fox test (successful vs unsuccessful). Results: Success in the Reverse Fox test was achieved by 31.9% of patients with AD and 94.4% of NL. The unsuccessful AD subgroup had reduced perfusion of the medial parietal and bilateral temporoparietal regions compared with the successful AD subgroup. Conclusions: Failure in the Reverse Fox test was related to parietal hypoperfusion in patients with mild AD. Our findings suggest that the Reverse Fox test may be one of the useful supporting tools for detecting mild AD at outpatient clinic.
AB - Background/Aim:We developed a novel visuospatial clinical task to detect parietal dysfunction in mild Alzheimers disease (AD). Methods: A total of 65 outpatients, including 47 with mild AD and 18 cognitively and neuroradiologically normal individuals with subjective memory impairment (NL), performed the Reverse Fox test and underwent brain single photon emission tomography. Patients with AD were divided into subgroups according to the results of the Reverse Fox test (successful vs unsuccessful). Results: Success in the Reverse Fox test was achieved by 31.9% of patients with AD and 94.4% of NL. The unsuccessful AD subgroup had reduced perfusion of the medial parietal and bilateral temporoparietal regions compared with the successful AD subgroup. Conclusions: Failure in the Reverse Fox test was related to parietal hypoperfusion in patients with mild AD. Our findings suggest that the Reverse Fox test may be one of the useful supporting tools for detecting mild AD at outpatient clinic.
KW - Alzheimer's disease
KW - gesture imitation
KW - screening test
KW - single photon emission computed tomography
KW - visuospatial abilities
UR - http://www.scopus.com/inward/record.url?scp=84898962339&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84898962339&partnerID=8YFLogxK
U2 - 10.1177/1533317513511291
DO - 10.1177/1533317513511291
M3 - Article
C2 - 24226465
AN - SCOPUS:84898962339
VL - 29
SP - 177
EP - 182
JO - American Journal of Alzheimer's Disease and other Dementias
JF - American Journal of Alzheimer's Disease and other Dementias
SN - 1533-3175
IS - 2
ER -