Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel

Erika Hasuike, Aya Mizutani Akimoto, Reiko Kuroda, Ko Matsukawa, Yuki Hiruta, Hideko Kanazawa, Ryo Yoshida

Research output: Contribution to journalArticle

12 Citations (Scopus)


The novel property of reversible regulation of parallel type G-quadruplexes with moderate temperature changes was discovered in thermoresponsive hydrogels using a universal chiroptical spectrophotometer 1 (UCS-1). This study is the first to report the regulation of the ssDNA steric structure by using a poly(N-isopropylacrylamide) (PNIPAAm) gel.

Original languageEnglish
Pages (from-to)3142-3144
Number of pages3
JournalChemical Communications
Issue number21
Publication statusPublished - 2017 Jan 1


ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this