Review of basic studies about the cardiac stem cell and regenerative medicine

Yuichi Tamura, Keiichi Fukuda

Research output: Contribution to journalReview article

Abstract

The availability of enough cardiomyocytes to transplant as a cardiac tissue is able to read the achievement of regenerative cardiac medicine. Tissue derived stem cells, embryonic stem (ES) cells and induced pluripotent stem (iPS) cells are all potential cell sources. Several types of cardiac tissue stem cells have already been reported, and we describe about the characteristics and multipotency of these tissue stem cells with an accurate comparison. ES cells and iPS cells are highly proliferative and suitable for mass production, and efficient protocols for selective cardiomyocyte induction using ES cells and iPS cells are also significant. On the other hand, these cells still have several issues about purification and safety as well as ethical problems.

Original languageEnglish
Pages (from-to)908-914
Number of pages7
JournalNippon rinsho. Japanese journal of clinical medicine
Volume66
Issue number5
Publication statusPublished - 2008 May

ASJC Scopus subject areas

  • Medicine(all)

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