Review of diagnosis and clinical course of retinoblastoma

Mayo Nozaki, Satoru Kase, Kazuhiko Yoshida, Kan Ishijima, Mika Noda, Shigenobu Suzuki, Noriyuki Azuma, Susumu Ishida

Research output: Contribution to journalArticle

Abstract

Purpose: To report 7 cases of retinoblastoma regarding initial diagnosis and clinical course. Cases: A retrospective study was made on 7 cases seen during the past 8 years. Results: The series comprised 2 boys and 5 girls. Five cases were unilaterally and two were bilaterally affected. Six cases were younger than 4 years and one was 7 years at the initial diagnosis. Chief complaints comprised leukocoria and squint in 5 cases, impaired vision in one, and hyperemia with edema of eyelid in one. Retinoblastoma was classified from stage B to E. Three eyes were in stage E at the time of diagnosis. Enucleation was performed in 5 eyes and orbital exenteration in one as the initial treatment. Enucleation became necessary in 2 out of 3 eyes that were conservatively treated. There was no metastasis in 6 eyes that received enucleation or exenteration. Two cases that developed extraocular infiltration resulted in fetal outcome. Initial clinical features in these 2 cases did not match with the final outcome. Conclusion: Clinical features of retinoblastoma at the initial diagnosis are not indicative of prognosis.

Original languageEnglish
Pages (from-to)1123-1127
Number of pages5
JournalJapanese Journal of Clinical Ophthalmology
Volume65
Issue number7
Publication statusPublished - 2011 Jul 15
Externally publishedYes

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Retinoblastoma
Eye Enucleation
Strabismus
Hyperemia
Eyelids
Edema
Retrospective Studies
Neoplasm Metastasis
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Nozaki, M., Kase, S., Yoshida, K., Ishijima, K., Noda, M., Suzuki, S., ... Ishida, S. (2011). Review of diagnosis and clinical course of retinoblastoma. Japanese Journal of Clinical Ophthalmology, 65(7), 1123-1127.

Review of diagnosis and clinical course of retinoblastoma. / Nozaki, Mayo; Kase, Satoru; Yoshida, Kazuhiko; Ishijima, Kan; Noda, Mika; Suzuki, Shigenobu; Azuma, Noriyuki; Ishida, Susumu.

In: Japanese Journal of Clinical Ophthalmology, Vol. 65, No. 7, 15.07.2011, p. 1123-1127.

Research output: Contribution to journalArticle

Nozaki, M, Kase, S, Yoshida, K, Ishijima, K, Noda, M, Suzuki, S, Azuma, N & Ishida, S 2011, 'Review of diagnosis and clinical course of retinoblastoma', Japanese Journal of Clinical Ophthalmology, vol. 65, no. 7, pp. 1123-1127.
Nozaki M, Kase S, Yoshida K, Ishijima K, Noda M, Suzuki S et al. Review of diagnosis and clinical course of retinoblastoma. Japanese Journal of Clinical Ophthalmology. 2011 Jul 15;65(7):1123-1127.
Nozaki, Mayo ; Kase, Satoru ; Yoshida, Kazuhiko ; Ishijima, Kan ; Noda, Mika ; Suzuki, Shigenobu ; Azuma, Noriyuki ; Ishida, Susumu. / Review of diagnosis and clinical course of retinoblastoma. In: Japanese Journal of Clinical Ophthalmology. 2011 ; Vol. 65, No. 7. pp. 1123-1127.
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