TY - JOUR
T1 - Review of synthetic MRI in pediatric brains
T2 - Basic principle of MR quantification, its features, clinical applications, and limitations
AU - Andica, Christina
AU - Hagiwara, Akifumi
AU - Hori, Masaaki
AU - Kamagata, Koji
AU - Koshino, Saori
AU - Maekawa, Tomoko
AU - Suzuki, Michimasa
AU - Fujiwara, Hirokazu
AU - Ikeno, Mitsuru
AU - Shimizu, Toshiaki
AU - Suzuki, Hiroharu
AU - Sugano, Hidenori
AU - Arai, Hajime
AU - Aoki, Shigeki
N1 - Funding Information:
This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (grant number 16K19852); by a JSPS Grant-in-Aid for Scientific Research on Innovative Areas, resource and technical support platforms for promoting research 'Advanced Bioimaging Support’ (grant number JP16H06280); by the Japan Radiological Society and Bayer Yakuhin (KJ-08); and by the Impulsing Paradigm Change through Disruptive Technologies (ImPACT) Program of the Council for Science, Technology and Innovation (Cabinet Office, Government of Japan).
Publisher Copyright:
© 2019 Elsevier Masson SAS
PY - 2019/7
Y1 - 2019/7
N2 - Quantitative magnetic resonance imaging (MRI)with multislice, multi-echo, and multi-delay acquisition enables simultaneous quantification of R1 and R2 relaxation rates, proton density, and the B1 field in a single acquisition, and requires only about 6 minutes for full-head coverage. Using dedicated SyMRI software, radiologists can generate any contrast-weighted image by manipulating the acquisition parameters, including repetition time, echo time, and inversion time. Moreover, automatic brain tissue segmentation, volumetry, and myelin measurement can also be performed. Using the SyMRI approach, a shorter scan time, an objective examination, and personalized MR imaging parameters can be obtained in daily clinical pediatric imaging. Here we summarize and review the use of SyMRI in imaging of the pediatric brain, including the basic principles of MR quantification along with its features, clinical applications, and limitations.
AB - Quantitative magnetic resonance imaging (MRI)with multislice, multi-echo, and multi-delay acquisition enables simultaneous quantification of R1 and R2 relaxation rates, proton density, and the B1 field in a single acquisition, and requires only about 6 minutes for full-head coverage. Using dedicated SyMRI software, radiologists can generate any contrast-weighted image by manipulating the acquisition parameters, including repetition time, echo time, and inversion time. Moreover, automatic brain tissue segmentation, volumetry, and myelin measurement can also be performed. Using the SyMRI approach, a shorter scan time, an objective examination, and personalized MR imaging parameters can be obtained in daily clinical pediatric imaging. Here we summarize and review the use of SyMRI in imaging of the pediatric brain, including the basic principles of MR quantification along with its features, clinical applications, and limitations.
KW - Automatic Brain tissue volumetry
KW - Brain development
KW - Myelin measurement
KW - Pediatric brain
KW - Quantitative MRI
KW - Synthetic MRI
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U2 - 10.1016/j.neurad.2019.02.005
DO - 10.1016/j.neurad.2019.02.005
M3 - Review article
C2 - 30853545
AN - SCOPUS:85063344785
SN - 0150-9861
VL - 46
SP - 268
EP - 275
JO - Journal of Neuroradiology
JF - Journal of Neuroradiology
IS - 4
ER -