Review of synthetic MRI in pediatric brains: Basic principle of MR quantification, its features, clinical applications, and limitations

Christina Andica, Akifumi Hagiwara, Masaaki Hori, Koji Kamagata, Saori Koshino, Tomoko Maekawa, Michimasa Suzuki, Hirokazu Fujiwara, Mitsuru Ikeno, Toshiaki Shimizu, Hiroharu Suzuki, Hidenori Sugano, Hajime Arai, Shigeki Aoki

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Quantitative magnetic resonance imaging (MRI) with multislice, multi-echo, and multi-delay acquisition enables simultaneous quantification of R 1 and R 2 relaxation rates, proton density, and the B 1 field in a single acquisition, and requires only about 6 minutes for full-head coverage. Using dedicated SyMRI software, radiologists can generate any contrast-weighted image by manipulating the acquisition parameters, including repetition time, echo time, and inversion time. Moreover, automatic brain tissue segmentation, volumetry, and myelin measurement can also be performed. Using the SyMRI approach, a shorter scan time, an objective examination, and personalized MR imaging parameters can be obtained in daily clinical pediatric imaging. Here we summarize and review the use of SyMRI in imaging of the pediatric brain, including the basic principles of MR quantification along with its features, clinical applications, and limitations.

Original languageEnglish
JournalJournal of Neuroradiology
DOIs
Publication statusPublished - 2019 Jan 1

Fingerprint

Magnetic Resonance Imaging
Pediatrics
Brain
Myelin Sheath
Neuroimaging
Protons
Software
Head

Keywords

  • Automatic Brain tissue volumetry
  • Brain development
  • Myelin measurement
  • Pediatric brain
  • Quantitative MRI
  • Synthetic MRI

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Review of synthetic MRI in pediatric brains : Basic principle of MR quantification, its features, clinical applications, and limitations. / Andica, Christina; Hagiwara, Akifumi; Hori, Masaaki; Kamagata, Koji; Koshino, Saori; Maekawa, Tomoko; Suzuki, Michimasa; Fujiwara, Hirokazu; Ikeno, Mitsuru; Shimizu, Toshiaki; Suzuki, Hiroharu; Sugano, Hidenori; Arai, Hajime; Aoki, Shigeki.

In: Journal of Neuroradiology, 01.01.2019.

Research output: Contribution to journalReview article

Andica, C, Hagiwara, A, Hori, M, Kamagata, K, Koshino, S, Maekawa, T, Suzuki, M, Fujiwara, H, Ikeno, M, Shimizu, T, Suzuki, H, Sugano, H, Arai, H & Aoki, S 2019, 'Review of synthetic MRI in pediatric brains: Basic principle of MR quantification, its features, clinical applications, and limitations', Journal of Neuroradiology. https://doi.org/10.1016/j.neurad.2019.02.005
Andica, Christina ; Hagiwara, Akifumi ; Hori, Masaaki ; Kamagata, Koji ; Koshino, Saori ; Maekawa, Tomoko ; Suzuki, Michimasa ; Fujiwara, Hirokazu ; Ikeno, Mitsuru ; Shimizu, Toshiaki ; Suzuki, Hiroharu ; Sugano, Hidenori ; Arai, Hajime ; Aoki, Shigeki. / Review of synthetic MRI in pediatric brains : Basic principle of MR quantification, its features, clinical applications, and limitations. In: Journal of Neuroradiology. 2019.
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