Rheumatoid neutrophilic dermatosis with tense blister formation

A case report and review of the literature

Yumi Fujio, Takeru Funakoshi, Kaori Nakayama, Masayuki Amagai, Manabu Ohyama

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We report a 78-year-old woman with rheumatoid neutrophilic dermatosis (RND) presenting with tense blisters; an extremely rare manifestation of this condition. Systemic corticosteroid was of limited efficacy, while dapsone was effective. A literature review of four similar cases showed that tense blisters in this type of RND tended to appear on the lower extremities of aged, female rheumatoid arthritis patients. Of note, half of the cases were resistant to corticosteroids, as anti-neutrophil agents are reported to be effective. Accordingly, it is important to recognise this unusual manifestation for the timely initiation of appropriate therapy.

Original languageEnglish
JournalAustralasian Journal of Dermatology
Volume55
Issue number1
DOIs
Publication statusPublished - 2014 Feb

Fingerprint

Blister
Skin Diseases
Adrenal Cortex Hormones
Dapsone
Lower Extremity
Rheumatoid Arthritis
Neutrophils
Therapeutics

Keywords

  • blister formation
  • bullous pemphigoid
  • neutrophilic dermatosis
  • rheumatoid arthritis

ASJC Scopus subject areas

  • Dermatology
  • Medicine(all)

Cite this

Rheumatoid neutrophilic dermatosis with tense blister formation : A case report and review of the literature. / Fujio, Yumi; Funakoshi, Takeru; Nakayama, Kaori; Amagai, Masayuki; Ohyama, Manabu.

In: Australasian Journal of Dermatology, Vol. 55, No. 1, 02.2014.

Research output: Contribution to journalArticle

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