Rhodium-Catalyzed Anti-Markovnikov Hydroamination of Aliphatic and Aromatic Terminal Alkynes with Aliphatic Primary Amines

Yoshihiko Morimoto, Takuya Kochi, Fumitoshi Kakiuchi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Anti-Markovnikov hydroamination of both aliphatic and aromatic terminal alkynes with primary amines was achieved using an 8-quinolinolato rhodium catalyst to form aldimines and enamines in high yields. This catalytic system realized high functional group tolerance including hydroxy, bromo, cyano, and thioester groups.

Original languageEnglish
JournalJournal of Organic Chemistry
DOIs
Publication statusAccepted/In press - 2021

ASJC Scopus subject areas

  • Organic Chemistry

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