Rhodium-catalyzed intermolecular [2 + 2] cycloaddition of terminal alkynes with electron-deficient alkenes

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

The first catalytic intermolecular [2 + 2] cycloaddition of terminal alkynes with electron-deficient alkenes is reported. The reaction proceeds with an 8-quinolinolato rhodium/phosphine catalyst system to give cyclobutenes from various substrates having polar functional groups in high yields with complete regioselectivity.

Original languageEnglish
Pages (from-to)1024-1027
Number of pages4
JournalOrganic Letters
Volume15
Issue number5
DOIs
Publication statusPublished - 2013

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phosphine
Regioselectivity
Rhodium
Alkynes
Cycloaddition
Cycloaddition Reaction
cycloaddition
Alkenes
alkynes
rhodium
phosphines
Functional groups
alkenes
Electrons
catalysts
Catalysts
Substrates
electrons

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Rhodium-catalyzed intermolecular [2 + 2] cycloaddition of terminal alkynes with electron-deficient alkenes. / Sakai, Kazunori; Kochi, Takuya; Kakiuchi, Fumitoshi.

In: Organic Letters, Vol. 15, No. 5, 2013, p. 1024-1027.

Research output: Contribution to journalArticle

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