Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension

Mitsushige Murata; Takashi Kawakami; Masaharu Kataoka; Takashi Kohno; Yuji Itabashi; Keiichi Fukuda

doi:10.1177/2045893217746111

Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension

Mitsushige Murata, Takashi Kawakami, Masaharu Kataoka, Takashi Kohno, Yuji Itabashi, Keiichi Fukuda

Research output: Contribution to journal › Letter › peer-review

7 Citations (Scopus)

Abstract

Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.

Original language	English
Journal	Pulmonary Circulation
Volume	8
Issue number	1
DOIs	https://doi.org/10.1177/2045893217746111
Publication status	Published - 2018 Jan 1

Keywords

Pulmonary hypertension
Right ventricular contraction
Riociguat

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1177/2045893217746111

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title = "Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension",

abstract = "Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.",

keywords = "Pulmonary hypertension, Right ventricular contraction, Riociguat",

author = "Mitsushige Murata and Takashi Kawakami and Masaharu Kataoka and Takashi Kohno and Yuji Itabashi and Keiichi Fukuda",

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doi = "10.1177/2045893217746111",

language = "English",

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AU - Murata, Mitsushige

AU - Kawakami, Takashi

AU - Kataoka, Masaharu

AU - Kohno, Takashi

AU - Itabashi, Yuji

AU - Fukuda, Keiichi

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.

AB - Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.

KW - Pulmonary hypertension

KW - Right ventricular contraction

KW - Riociguat

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U2 - 10.1177/2045893217746111

DO - 10.1177/2045893217746111

M3 - Letter

AN - SCOPUS:85041391326

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VL - 8

JO - Pulmonary Circulation

JF - Pulmonary Circulation

IS - 1

ER -

Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension

Abstract

Keywords

ASJC Scopus subject areas

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