Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension

Mitsushige Murata, Takashi Kawakami, Masaharu Kataoka, Takashi Kohno, Yuji Itabashi, Keiichi Fukuda

Research output: Contribution to journalLetter

4 Citations (Scopus)

Abstract

Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.

Original languageEnglish
JournalPulmonary Circulation
Volume8
Issue number1
DOIs
Publication statusPublished - 2018 Jan 1

Keywords

  • Pulmonary hypertension
  • Right ventricular contraction
  • Riociguat

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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