Risk Factor Effects and Total Mortality in Older Japanese Men in Japan and Hawaii

Robert D. Abbott, Hirotsugu Ueshima, Atsushi Hozawa, Tomonori Okamura, Takashi Kadowaki, Katsuyuki Miura, Nagako Okuda, Yasuyuki Nakamura, Akira Okayama, Yoshikuni Kita, Beatriz L. Rodriguez, Katsuhiko Yano, J. David Curb

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

purpose: We sought to identify factors related to total mortality in older Japanese men in Japan and Hawaii. Methods: Baseline data were collected from 1980 to 1982 in 1379 men in Hawaii and 954 men in Japan. Ages ranged from 61 to 81 years, with mortality follow-up during a 19-year period. Results: Compared with Japan, men in Hawaii had a 2-fold excess of diabetes and a 4-fold excess of prevalent coronary heart disease (P < .001). Total cholesterol and body mass index were also greater in Hawaiian men (P < .001). In contrast, men in Japan had greater systolic blood pressure and were nearly 3 times more likely to smoke cigarettes (P < .001). Although each cohort had elements of a poor risk factor profile, there was a 1.4-fold excess in the risk of death in Japan (49.4 vs. 36.2/1,000 person-years, P < .001). Although mortality was similar after risk factor adjustment, only blood pressure and cigarette smoking accounted for the higher risk of death in Japan. Conclusions: Cigarette smoking and hypertension explain much of the excess mortality in Japan versus Hawaii. In this comparison of genetically similar cohorts, evidence further suggests that Japanese in Japan are equally susceptible to develop the same adverse risk factor conditions that exist in Hawaii.

Original languageEnglish
Pages (from-to)913-918
Number of pages6
JournalAnnals of Epidemiology
Volume18
Issue number12
DOIs
Publication statusPublished - 2008 Dec
Externally publishedYes

Fingerprint

Japan
Mortality
Blood Pressure
Smoking
Risk Adjustment
Smoke
Tobacco Products
Coronary Disease
Body Mass Index
Cholesterol
Hypertension

Keywords

  • Epidemiology
  • Japanese
  • Mortality
  • Risk factor

ASJC Scopus subject areas

  • Epidemiology

Cite this

Abbott, R. D., Ueshima, H., Hozawa, A., Okamura, T., Kadowaki, T., Miura, K., ... Curb, J. D. (2008). Risk Factor Effects and Total Mortality in Older Japanese Men in Japan and Hawaii. Annals of Epidemiology, 18(12), 913-918. https://doi.org/10.1016/j.annepidem.2008.09.004

Risk Factor Effects and Total Mortality in Older Japanese Men in Japan and Hawaii. / Abbott, Robert D.; Ueshima, Hirotsugu; Hozawa, Atsushi; Okamura, Tomonori; Kadowaki, Takashi; Miura, Katsuyuki; Okuda, Nagako; Nakamura, Yasuyuki; Okayama, Akira; Kita, Yoshikuni; Rodriguez, Beatriz L.; Yano, Katsuhiko; Curb, J. David.

In: Annals of Epidemiology, Vol. 18, No. 12, 12.2008, p. 913-918.

Research output: Contribution to journalArticle

Abbott, RD, Ueshima, H, Hozawa, A, Okamura, T, Kadowaki, T, Miura, K, Okuda, N, Nakamura, Y, Okayama, A, Kita, Y, Rodriguez, BL, Yano, K & Curb, JD 2008, 'Risk Factor Effects and Total Mortality in Older Japanese Men in Japan and Hawaii', Annals of Epidemiology, vol. 18, no. 12, pp. 913-918. https://doi.org/10.1016/j.annepidem.2008.09.004
Abbott, Robert D. ; Ueshima, Hirotsugu ; Hozawa, Atsushi ; Okamura, Tomonori ; Kadowaki, Takashi ; Miura, Katsuyuki ; Okuda, Nagako ; Nakamura, Yasuyuki ; Okayama, Akira ; Kita, Yoshikuni ; Rodriguez, Beatriz L. ; Yano, Katsuhiko ; Curb, J. David. / Risk Factor Effects and Total Mortality in Older Japanese Men in Japan and Hawaii. In: Annals of Epidemiology. 2008 ; Vol. 18, No. 12. pp. 913-918.
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