Risk factors for anxiety and depression in patients with glaucoma

Fumihiko Mabuchi, Kimio Yoshimura, Kenji Kashiwagi, Zentaro Yamagata, Shigenobu Kanba, Hiroyuki Iijima, Shigeo Tsukahara

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Aim: To assess the risk factors for anxiety and depression in patients with glaucoma. Methods: Anxiety and depression in 408 patients with glaucoma were evaluated using the hospital anxiety and depression scale (HADS) questionnaire, which consists of two subscales, representing HADS-anxiety (HADS-A) and HADS-depression (HADS-D). To identify the risk factors for anxiety and depression, the stepwise and multiple linear regression analyses were carried out with the HADS-A and HADS-D subscores as dependent variables and demographic and clinical features as independent variables. Results: A stepwise linear regression analysis revealed the significantly related factors to be age for HADS-A (β=-0.046, p=0.0007) and HADS-D (β=0.035, p=0.011) and the mean deviation of the Humphrey Visual Field Analyzer 30-2 (HFA30-2) in the better eye for HADS-D (β=-0.095, p=0.0026). Based on multiple linear regression analyses, significant relationships were confirmed between age and the HADS-A subscore (β=-0.046, p=0.0008). Significant relationships were also confirmed between age (β=0.037, p=0.0077) or the mean deviation of HFA30-2 in the better eye (β=-0.094, p=0.0036) and the HADS-D subscore. Conclusion: A younger age was thus found to be a risk factor for anxiety, while an older age and increasing glaucoma severity were risk factors for depression in patients with glaucoma.

Original languageEnglish
Pages (from-to)821-825
Number of pages5
JournalBritish Journal of Ophthalmology
Volume96
Issue number6
DOIs
Publication statusPublished - 2012 Jun

Fingerprint

Glaucoma
Anxiety
Depression
Linear Models
Regression Analysis
Visual Fields

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Mabuchi, F., Yoshimura, K., Kashiwagi, K., Yamagata, Z., Kanba, S., Iijima, H., & Tsukahara, S. (2012). Risk factors for anxiety and depression in patients with glaucoma. British Journal of Ophthalmology, 96(6), 821-825. https://doi.org/10.1136/bjophthalmol-2011-300910

Risk factors for anxiety and depression in patients with glaucoma. / Mabuchi, Fumihiko; Yoshimura, Kimio; Kashiwagi, Kenji; Yamagata, Zentaro; Kanba, Shigenobu; Iijima, Hiroyuki; Tsukahara, Shigeo.

In: British Journal of Ophthalmology, Vol. 96, No. 6, 06.2012, p. 821-825.

Research output: Contribution to journalArticle

Mabuchi, F, Yoshimura, K, Kashiwagi, K, Yamagata, Z, Kanba, S, Iijima, H & Tsukahara, S 2012, 'Risk factors for anxiety and depression in patients with glaucoma', British Journal of Ophthalmology, vol. 96, no. 6, pp. 821-825. https://doi.org/10.1136/bjophthalmol-2011-300910
Mabuchi, Fumihiko ; Yoshimura, Kimio ; Kashiwagi, Kenji ; Yamagata, Zentaro ; Kanba, Shigenobu ; Iijima, Hiroyuki ; Tsukahara, Shigeo. / Risk factors for anxiety and depression in patients with glaucoma. In: British Journal of Ophthalmology. 2012 ; Vol. 96, No. 6. pp. 821-825.
@article{22a6c2396f5e41049b86a6f4359a3314,
title = "Risk factors for anxiety and depression in patients with glaucoma",
abstract = "Aim: To assess the risk factors for anxiety and depression in patients with glaucoma. Methods: Anxiety and depression in 408 patients with glaucoma were evaluated using the hospital anxiety and depression scale (HADS) questionnaire, which consists of two subscales, representing HADS-anxiety (HADS-A) and HADS-depression (HADS-D). To identify the risk factors for anxiety and depression, the stepwise and multiple linear regression analyses were carried out with the HADS-A and HADS-D subscores as dependent variables and demographic and clinical features as independent variables. Results: A stepwise linear regression analysis revealed the significantly related factors to be age for HADS-A (β=-0.046, p=0.0007) and HADS-D (β=0.035, p=0.011) and the mean deviation of the Humphrey Visual Field Analyzer 30-2 (HFA30-2) in the better eye for HADS-D (β=-0.095, p=0.0026). Based on multiple linear regression analyses, significant relationships were confirmed between age and the HADS-A subscore (β=-0.046, p=0.0008). Significant relationships were also confirmed between age (β=0.037, p=0.0077) or the mean deviation of HFA30-2 in the better eye (β=-0.094, p=0.0036) and the HADS-D subscore. Conclusion: A younger age was thus found to be a risk factor for anxiety, while an older age and increasing glaucoma severity were risk factors for depression in patients with glaucoma.",
author = "Fumihiko Mabuchi and Kimio Yoshimura and Kenji Kashiwagi and Zentaro Yamagata and Shigenobu Kanba and Hiroyuki Iijima and Shigeo Tsukahara",
year = "2012",
month = "6",
doi = "10.1136/bjophthalmol-2011-300910",
language = "English",
volume = "96",
pages = "821--825",
journal = "British Journal of Ophthalmology",
issn = "0007-1161",
publisher = "BMJ Publishing Group",
number = "6",

}

TY - JOUR

T1 - Risk factors for anxiety and depression in patients with glaucoma

AU - Mabuchi, Fumihiko

AU - Yoshimura, Kimio

AU - Kashiwagi, Kenji

AU - Yamagata, Zentaro

AU - Kanba, Shigenobu

AU - Iijima, Hiroyuki

AU - Tsukahara, Shigeo

PY - 2012/6

Y1 - 2012/6

N2 - Aim: To assess the risk factors for anxiety and depression in patients with glaucoma. Methods: Anxiety and depression in 408 patients with glaucoma were evaluated using the hospital anxiety and depression scale (HADS) questionnaire, which consists of two subscales, representing HADS-anxiety (HADS-A) and HADS-depression (HADS-D). To identify the risk factors for anxiety and depression, the stepwise and multiple linear regression analyses were carried out with the HADS-A and HADS-D subscores as dependent variables and demographic and clinical features as independent variables. Results: A stepwise linear regression analysis revealed the significantly related factors to be age for HADS-A (β=-0.046, p=0.0007) and HADS-D (β=0.035, p=0.011) and the mean deviation of the Humphrey Visual Field Analyzer 30-2 (HFA30-2) in the better eye for HADS-D (β=-0.095, p=0.0026). Based on multiple linear regression analyses, significant relationships were confirmed between age and the HADS-A subscore (β=-0.046, p=0.0008). Significant relationships were also confirmed between age (β=0.037, p=0.0077) or the mean deviation of HFA30-2 in the better eye (β=-0.094, p=0.0036) and the HADS-D subscore. Conclusion: A younger age was thus found to be a risk factor for anxiety, while an older age and increasing glaucoma severity were risk factors for depression in patients with glaucoma.

AB - Aim: To assess the risk factors for anxiety and depression in patients with glaucoma. Methods: Anxiety and depression in 408 patients with glaucoma were evaluated using the hospital anxiety and depression scale (HADS) questionnaire, which consists of two subscales, representing HADS-anxiety (HADS-A) and HADS-depression (HADS-D). To identify the risk factors for anxiety and depression, the stepwise and multiple linear regression analyses were carried out with the HADS-A and HADS-D subscores as dependent variables and demographic and clinical features as independent variables. Results: A stepwise linear regression analysis revealed the significantly related factors to be age for HADS-A (β=-0.046, p=0.0007) and HADS-D (β=0.035, p=0.011) and the mean deviation of the Humphrey Visual Field Analyzer 30-2 (HFA30-2) in the better eye for HADS-D (β=-0.095, p=0.0026). Based on multiple linear regression analyses, significant relationships were confirmed between age and the HADS-A subscore (β=-0.046, p=0.0008). Significant relationships were also confirmed between age (β=0.037, p=0.0077) or the mean deviation of HFA30-2 in the better eye (β=-0.094, p=0.0036) and the HADS-D subscore. Conclusion: A younger age was thus found to be a risk factor for anxiety, while an older age and increasing glaucoma severity were risk factors for depression in patients with glaucoma.

UR - http://www.scopus.com/inward/record.url?scp=84861329547&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861329547&partnerID=8YFLogxK

U2 - 10.1136/bjophthalmol-2011-300910

DO - 10.1136/bjophthalmol-2011-300910

M3 - Article

C2 - 22353697

AN - SCOPUS:84861329547

VL - 96

SP - 821

EP - 825

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

SN - 0007-1161

IS - 6

ER -