Risk factors for complications after pharyngolaryngectomy with total esophagectomy

Eisuke Booka, Yasuhiro Tsubosa, Masahiro Niihara, Wataru Takagi, Katsushi Takebayashi, Ayako Shimada, Takashi Kitani, Masato Nagaoka, Atsushi Imai, Tomoyuki Kamijo, Yoshiyuki Iida, Tetsuro Onitsuka, Masahiro Nakagawa, Hiroya Takeuchi, Yuukou Kitagawa

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Pharyngolaryngectomy with total esophagectomy (PLTE) is an effective surgical treatment for synchronous or metachronous hypopharyngeal or laryngeal cancer and thoracic esophageal cancer, although it is more invasive than esophagectomy and total pharyngolaryngectomy. The aim of this study was to identify risk factors for complications after PLTE. Methods: From November 2002 to December 2014, a total of 8 patients underwent PLTE at the Shizuoka Cancer Center Hospital, Shizuoka, Japan. We investigated the clinicopathological characteristics, surgical procedures, and postoperative complications of these patients. Results: Of the 8 patients, 5 underwent one-stage PLTE and 3 underwent staged PLTE. There was no mortality in this study. Two cases of tracheal necrosis, two of anastomotic leakage, and one of ileus were observed as postoperative complications. Two patients who underwent one-stage PLTE with standard mediastinal lymph node dissection developed tracheal necrosis and severe anastomotic leakage. Conclusion: One-stage PLTE and standard mediastinal lymph node dissection were identified as the risk factors for severe postoperative complications. Staged PLTE or transhiatal esophagectomy should be considered when PLTE is performed and standard mediastinal lymph node dissection should be avoided when one-stage PLTE is performed with transthoracic esophagectomy.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalEsophagus
DOIs
Publication statusAccepted/In press - 2016 Mar 31

Fingerprint

Esophagectomy
Lymph Node Excision
Anastomotic Leak
Necrosis
Hypopharyngeal Neoplasms
Cancer Care Facilities
Laryngeal Neoplasms
Ileus
Esophageal Neoplasms
Japan
Thorax

Keywords

  • Esophageal cancer
  • Hypopharyngeal cancer
  • Pharyngolaryngectomy
  • Total esophagectomy
  • Tracheal necrosis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Booka, E., Tsubosa, Y., Niihara, M., Takagi, W., Takebayashi, K., Shimada, A., ... Kitagawa, Y. (Accepted/In press). Risk factors for complications after pharyngolaryngectomy with total esophagectomy. Esophagus, 1-6. https://doi.org/10.1007/s10388-016-0533-9

Risk factors for complications after pharyngolaryngectomy with total esophagectomy. / Booka, Eisuke; Tsubosa, Yasuhiro; Niihara, Masahiro; Takagi, Wataru; Takebayashi, Katsushi; Shimada, Ayako; Kitani, Takashi; Nagaoka, Masato; Imai, Atsushi; Kamijo, Tomoyuki; Iida, Yoshiyuki; Onitsuka, Tetsuro; Nakagawa, Masahiro; Takeuchi, Hiroya; Kitagawa, Yuukou.

In: Esophagus, 31.03.2016, p. 1-6.

Research output: Contribution to journalArticle

Booka, E, Tsubosa, Y, Niihara, M, Takagi, W, Takebayashi, K, Shimada, A, Kitani, T, Nagaoka, M, Imai, A, Kamijo, T, Iida, Y, Onitsuka, T, Nakagawa, M, Takeuchi, H & Kitagawa, Y 2016, 'Risk factors for complications after pharyngolaryngectomy with total esophagectomy', Esophagus, pp. 1-6. https://doi.org/10.1007/s10388-016-0533-9
Booka E, Tsubosa Y, Niihara M, Takagi W, Takebayashi K, Shimada A et al. Risk factors for complications after pharyngolaryngectomy with total esophagectomy. Esophagus. 2016 Mar 31;1-6. https://doi.org/10.1007/s10388-016-0533-9
Booka, Eisuke ; Tsubosa, Yasuhiro ; Niihara, Masahiro ; Takagi, Wataru ; Takebayashi, Katsushi ; Shimada, Ayako ; Kitani, Takashi ; Nagaoka, Masato ; Imai, Atsushi ; Kamijo, Tomoyuki ; Iida, Yoshiyuki ; Onitsuka, Tetsuro ; Nakagawa, Masahiro ; Takeuchi, Hiroya ; Kitagawa, Yuukou. / Risk factors for complications after pharyngolaryngectomy with total esophagectomy. In: Esophagus. 2016 ; pp. 1-6.
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abstract = "Background: Pharyngolaryngectomy with total esophagectomy (PLTE) is an effective surgical treatment for synchronous or metachronous hypopharyngeal or laryngeal cancer and thoracic esophageal cancer, although it is more invasive than esophagectomy and total pharyngolaryngectomy. The aim of this study was to identify risk factors for complications after PLTE. Methods: From November 2002 to December 2014, a total of 8 patients underwent PLTE at the Shizuoka Cancer Center Hospital, Shizuoka, Japan. We investigated the clinicopathological characteristics, surgical procedures, and postoperative complications of these patients. Results: Of the 8 patients, 5 underwent one-stage PLTE and 3 underwent staged PLTE. There was no mortality in this study. Two cases of tracheal necrosis, two of anastomotic leakage, and one of ileus were observed as postoperative complications. Two patients who underwent one-stage PLTE with standard mediastinal lymph node dissection developed tracheal necrosis and severe anastomotic leakage. Conclusion: One-stage PLTE and standard mediastinal lymph node dissection were identified as the risk factors for severe postoperative complications. Staged PLTE or transhiatal esophagectomy should be considered when PLTE is performed and standard mediastinal lymph node dissection should be avoided when one-stage PLTE is performed with transthoracic esophagectomy.",
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author = "Eisuke Booka and Yasuhiro Tsubosa and Masahiro Niihara and Wataru Takagi and Katsushi Takebayashi and Ayako Shimada and Takashi Kitani and Masato Nagaoka and Atsushi Imai and Tomoyuki Kamijo and Yoshiyuki Iida and Tetsuro Onitsuka and Masahiro Nakagawa and Hiroya Takeuchi and Yuukou Kitagawa",
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AU - Takebayashi, Katsushi

AU - Shimada, Ayako

AU - Kitani, Takashi

AU - Nagaoka, Masato

AU - Imai, Atsushi

AU - Kamijo, Tomoyuki

AU - Iida, Yoshiyuki

AU - Onitsuka, Tetsuro

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AU - Takeuchi, Hiroya

AU - Kitagawa, Yuukou

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