Robustness of suspended bilayer lipid membrane for portable sensor applications

L. N S Zaleha, T. Osaki, R. Kawano, K. Kamiya, Norihisa Miki, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

We examined the robustness of suspended bilayer lipid membranes (BLMs), aiming for portable sensor systems. BLMs are highly likely to rapture at their natural frequencies, therefore the natural frequencies of BLMs need to be set above the frequencies of vibration that the sensor experience during operation. We used a micro split-and-contact device to form BLMs with good reproducibility and applied the device to vibration tests to deduce the natural frequency, where we investigated the BLMs area and the incorporation of a nanopore-forming protein into BLMs. We conclude that larger BLMs area and the protein incorporation decreases the natural frequency of BLMs.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages701-702
Number of pages2
ISBN (Print)9780979806476
Publication statusPublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period14/10/2614/10/30

Fingerprint

Lipid bilayers
Sensors
Natural frequencies
Proteins
Nanopores
Membrane Lipids
Vibrations (mechanical)

Keywords

  • Membrane stability
  • Natural frequency
  • Vibration test

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Zaleha, L. N. S., Osaki, T., Kawano, R., Kamiya, K., Miki, N., & Takeuchi, S. (2014). Robustness of suspended bilayer lipid membrane for portable sensor applications. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 701-702). Chemical and Biological Microsystems Society.

Robustness of suspended bilayer lipid membrane for portable sensor applications. / Zaleha, L. N S; Osaki, T.; Kawano, R.; Kamiya, K.; Miki, Norihisa; Takeuchi, S.

18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. p. 701-702.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zaleha, LNS, Osaki, T, Kawano, R, Kamiya, K, Miki, N & Takeuchi, S 2014, Robustness of suspended bilayer lipid membrane for portable sensor applications. in 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, pp. 701-702, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, United States, 14/10/26.
Zaleha LNS, Osaki T, Kawano R, Kamiya K, Miki N, Takeuchi S. Robustness of suspended bilayer lipid membrane for portable sensor applications. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society. 2014. p. 701-702
Zaleha, L. N S ; Osaki, T. ; Kawano, R. ; Kamiya, K. ; Miki, Norihisa ; Takeuchi, S. / Robustness of suspended bilayer lipid membrane for portable sensor applications. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. pp. 701-702
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