[Roles of lipid mediators in controlling vascular inflammation and the progression of atherosclerosis].

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Atherosclerosis is recognized as an inflammatory condition of the vessel wall, characterized by accumulation of inflammatory cells such as macrophages and T cells. There are accumulating evidences that chemokines, cytokines, and lipid mediators coordinately modulate platelet- or leukocyte-endothelial cell interactions, and contribute to the maintenance of vascular homeostasis. This review focuses on the role of lipid mediators, especially those derived from polyunsaturated fatty acids, in controlling vascular inflammation and the progression of atherosclerosis.

Original languageEnglish
Pages (from-to)34-38
Number of pages5
JournalNippon rinsho. Japanese journal of clinical medicine
Issue number1
Publication statusPublished - 2011 Jan 1
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)

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