Ruthenium-catalyzed acylation of arylpyridines with acyl chlorides via ortho-selective CH bond cleavage

Takuya Kochi, Aoi Tazawa, Kazuki Honda, Fumitoshi Kakiuchi

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Abstract

Ruthenium-catalyzed ortho-selective acylation of arylpyridines with acyl chlorides via CH bond cleavage is described. Aromatic acyl chlorides as well as α,β-unsaturated acyl chlorides were coupled with arylpyridines to give aromatic ketones in the presence of [RuCl2(PPh3) 3] as a catalyst and potassium carbonate as a base.

Original languageEnglish
Pages (from-to)1018-1020
Number of pages3
JournalChemistry Letters
Volume40
Issue number9
DOIs
Publication statusPublished - 2011

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ASJC Scopus subject areas

  • Chemistry(all)

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