Ruthenium-catalyzed ortho-selective acylation of arylpyridines with acyl chlorides via CH bond cleavage is described. Aromatic acyl chlorides as well as α,β-unsaturated acyl chlorides were coupled with arylpyridines to give aromatic ketones in the presence of [RuCl2(PPh3) 3] as a catalyst and potassium carbonate as a base.
|Number of pages||3|
|Publication status||Published - 2011|
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