Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles. Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds

Taku Asaumi; Naoto Chatani; Takuya Matsuo; Fumitoshi Kakiuchi; Shinji Murai

Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles. Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds

Taku Asaumi, Naoto Chatani, Takuya Matsuo, Fumitoshi Kakiuchi, Shinji Murai

Research output: Contribution to journal › Article

Abstract

The reaction of 1-arylpyrazoles with CO and ethylene in the presence of Ru₃(CO)₁₂ resulted in regioselective carbonylation at the ortho C-H bonds. While it is found that the pyrazole ring also functions as the directing group for C-H bond cleavage, the efficiency of the reaction depends on the position of the pyrazole ring.

Original language	English
Pages (from-to)	7538-7540
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	68
Issue number	19
Publication status	Published - 2003 Sep 19
Externally published	Yes

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Organic Chemistry

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Asaumi, T., Chatani, N., Matsuo, T., Kakiuchi, F., & Murai, S. (2003). Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles. Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds. Journal of Organic Chemistry, 68(19), 7538-7540.

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abstract = "The reaction of 1-arylpyrazoles with CO and ethylene in the presence of Ru3(CO)12 resulted in regioselective carbonylation at the ortho C-H bonds. While it is found that the pyrazole ring also functions as the directing group for C-H bond cleavage, the efficiency of the reaction depends on the position of the pyrazole ring.",

author = "Taku Asaumi and Naoto Chatani and Takuya Matsuo and Fumitoshi Kakiuchi and Shinji Murai",

year = "2003",

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T1 - Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles. Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds

AU - Asaumi, Taku

AU - Chatani, Naoto

AU - Matsuo, Takuya

AU - Kakiuchi, Fumitoshi

AU - Murai, Shinji

PY - 2003/9/19

Y1 - 2003/9/19

N2 - The reaction of 1-arylpyrazoles with CO and ethylene in the presence of Ru3(CO)12 resulted in regioselective carbonylation at the ortho C-H bonds. While it is found that the pyrazole ring also functions as the directing group for C-H bond cleavage, the efficiency of the reaction depends on the position of the pyrazole ring.

AB - The reaction of 1-arylpyrazoles with CO and ethylene in the presence of Ru3(CO)12 resulted in regioselective carbonylation at the ortho C-H bonds. While it is found that the pyrazole ring also functions as the directing group for C-H bond cleavage, the efficiency of the reaction depends on the position of the pyrazole ring.

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Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles. Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds

Abstract

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