Abstract
Ru-catalyzed cycloisomerization of a 1,3-diene and the alkene of an N-dienyl-2-vinylaniline substrate proceeded smoothly, leading to a 3-exomethylene-2-vinylindole derivative in good yield. This useful synthon was successfully applied to the total synthesis of (±)-cinchonaminone.
| Original language | English |
|---|---|
| Pages (from-to) | 3084-3087 |
| Number of pages | 4 |
| Journal | European Journal of Organic Chemistry |
| Issue number | 16 |
| DOIs | |
| Publication status | Published - 2012 Jun |
| Externally published | Yes |
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Keywords
- Cyclization
- Heterocycles
- Natural products
- Ruthenium
- Total synthesis
ASJC Scopus subject areas
- Organic Chemistry
- Physical and Theoretical Chemistry
Cite this
Ruthenium-catalyzed cycloisomerization and its application to the synthesis of (±)-cinchonaminone. / Ogawa, Takao; Nakamura, Tomonori; Araki, Takuya; Yamamoto, Koujirou; Shuto, Satoshi; Arisawa, Mitsuhiro.
In: European Journal of Organic Chemistry, No. 16, 06.2012, p. 3084-3087.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ruthenium-catalyzed cycloisomerization and its application to the synthesis of (±)-cinchonaminone
AU - Ogawa, Takao
AU - Nakamura, Tomonori
AU - Araki, Takuya
AU - Yamamoto, Koujirou
AU - Shuto, Satoshi
AU - Arisawa, Mitsuhiro
PY - 2012/6
Y1 - 2012/6
N2 - Ru-catalyzed cycloisomerization of a 1,3-diene and the alkene of an N-dienyl-2-vinylaniline substrate proceeded smoothly, leading to a 3-exomethylene-2-vinylindole derivative in good yield. This useful synthon was successfully applied to the total synthesis of (±)-cinchonaminone.
AB - Ru-catalyzed cycloisomerization of a 1,3-diene and the alkene of an N-dienyl-2-vinylaniline substrate proceeded smoothly, leading to a 3-exomethylene-2-vinylindole derivative in good yield. This useful synthon was successfully applied to the total synthesis of (±)-cinchonaminone.
KW - Cyclization
KW - Heterocycles
KW - Natural products
KW - Ruthenium
KW - Total synthesis
UR - http://www.scopus.com/inward/record.url?scp=84862080077&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862080077&partnerID=8YFLogxK
U2 - 10.1002/ejoc.201200260
DO - 10.1002/ejoc.201200260
M3 - Article
AN - SCOPUS:84862080077
SP - 3084
EP - 3087
JO - Annalen der Pharmacie
JF - Annalen der Pharmacie
SN - 0365-5490
IS - 16
ER -