Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection

Mitsuhiro Fujishiro, Naohisa Yahagi, Masanori Nakamura, Naomi Kakushima, Shinya Kodashima, Satoshi Ono, Katsuya Kobayashi, Takuhei Hashimoto, Nobutake Yamamichi, Ayako Tateishi, Yasuhito Shimizu, Masashi Oka, Masao Ichinose, Masao Omata

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline injection and without injection. Only subtle tissue damage was observed in the injection group, whereas apparent damage was observed in the noninjection group. The damaged distances in depth significantly increased as the pulse duration increased and those at the pulse duration of 4 seconds, which might be maximal in clinical practice, were approximately 1 mm. As an in vivo study, APC was applied over mucosal defects immediately after EMR. Only subtle tissue damage was observed even at the pulse duration of 20 seconds as shown in the ex vivo study. APC can be performed safely over the mucosal defects during/after EMR.

Original languageEnglish
Pages (from-to)137-140
Number of pages4
JournalSurgical Laparoscopy, Endoscopy and Percutaneous Techniques
Volume16
Issue number3
DOIs
Publication statusPublished - 2006 Jun
Externally publishedYes

Fingerprint

Argon Plasma Coagulation
Hemostasis
Safety
Injections
Miniature Swine
Stomach
Swine
Endoscopic Mucosal Resection

Keywords

  • Argon plasma coagulation
  • Endoscopic mucosal resection
  • Hemostasis
  • Tissue damage

ASJC Scopus subject areas

  • Surgery

Cite this

Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection. / Fujishiro, Mitsuhiro; Yahagi, Naohisa; Nakamura, Masanori; Kakushima, Naomi; Kodashima, Shinya; Ono, Satoshi; Kobayashi, Katsuya; Hashimoto, Takuhei; Yamamichi, Nobutake; Tateishi, Ayako; Shimizu, Yasuhito; Oka, Masashi; Ichinose, Masao; Omata, Masao.

In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, Vol. 16, No. 3, 06.2006, p. 137-140.

Research output: Contribution to journalArticle

Fujishiro, M, Yahagi, N, Nakamura, M, Kakushima, N, Kodashima, S, Ono, S, Kobayashi, K, Hashimoto, T, Yamamichi, N, Tateishi, A, Shimizu, Y, Oka, M, Ichinose, M & Omata, M 2006, 'Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection', Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, vol. 16, no. 3, pp. 137-140. https://doi.org/10.1097/00129689-200606000-00003
Fujishiro, Mitsuhiro ; Yahagi, Naohisa ; Nakamura, Masanori ; Kakushima, Naomi ; Kodashima, Shinya ; Ono, Satoshi ; Kobayashi, Katsuya ; Hashimoto, Takuhei ; Yamamichi, Nobutake ; Tateishi, Ayako ; Shimizu, Yasuhito ; Oka, Masashi ; Ichinose, Masao ; Omata, Masao. / Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection. In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 2006 ; Vol. 16, No. 3. pp. 137-140.
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