TY - JOUR
T1 - Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection
AU - Fujishiro, Mitsuhiro
AU - Yahagi, Naohisa
AU - Nakamura, Masanori
AU - Kakushima, Naomi
AU - Kodashima, Shinya
AU - Ono, Satoshi
AU - Kobayashi, Katsuya
AU - Hashimoto, Takuhei
AU - Yamamichi, Nobutake
AU - Tateishi, Ayako
AU - Shimizu, Yasuhito
AU - Oka, Masashi
AU - Ichinose, Masao
AU - Omata, Masao
PY - 2006/6
Y1 - 2006/6
N2 - Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline injection and without injection. Only subtle tissue damage was observed in the injection group, whereas apparent damage was observed in the noninjection group. The damaged distances in depth significantly increased as the pulse duration increased and those at the pulse duration of 4 seconds, which might be maximal in clinical practice, were approximately 1 mm. As an in vivo study, APC was applied over mucosal defects immediately after EMR. Only subtle tissue damage was observed even at the pulse duration of 20 seconds as shown in the ex vivo study. APC can be performed safely over the mucosal defects during/after EMR.
AB - Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline injection and without injection. Only subtle tissue damage was observed in the injection group, whereas apparent damage was observed in the noninjection group. The damaged distances in depth significantly increased as the pulse duration increased and those at the pulse duration of 4 seconds, which might be maximal in clinical practice, were approximately 1 mm. As an in vivo study, APC was applied over mucosal defects immediately after EMR. Only subtle tissue damage was observed even at the pulse duration of 20 seconds as shown in the ex vivo study. APC can be performed safely over the mucosal defects during/after EMR.
KW - Argon plasma coagulation
KW - Endoscopic mucosal resection
KW - Hemostasis
KW - Tissue damage
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U2 - 10.1097/00129689-200606000-00003
DO - 10.1097/00129689-200606000-00003
M3 - Article
C2 - 16804454
AN - SCOPUS:33748145103
VL - 16
SP - 137
EP - 140
JO - Surgical Laparoscopy, Endoscopy and Percutaneous Techniques
JF - Surgical Laparoscopy, Endoscopy and Percutaneous Techniques
SN - 1530-4515
IS - 3
ER -