Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection

Mitsuhiro Fujishiro; Naohisa Yahagi; Masanori Nakamura; Naomi Kakushima; Shinya Kodashima; Satoshi Ono; Katsuya Kobayashi; Takuhei Hashimoto; Nobutake Yamamichi; Ayako Tateishi; Yasuhito Shimizu; Masashi Oka; Masao Ichinose; Masao Omata

doi:10.1097/00129689-200606000-00003

Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection

Mitsuhiro Fujishiro, Naohisa Yahagi, Masanori Nakamura, Naomi Kakushima, Shinya Kodashima, Satoshi Ono, Katsuya Kobayashi, Takuhei Hashimoto, Nobutake Yamamichi, Ayako Tateishi, Yasuhito Shimizu, Masashi Oka, Masao Ichinose, Masao Omata

Cancer Center (Advanced Minimally Invasive Therapy Unit)

Research output: Contribution to journal › Article

13 Citations (Scopus)

Abstract

Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline injection and without injection. Only subtle tissue damage was observed in the injection group, whereas apparent damage was observed in the noninjection group. The damaged distances in depth significantly increased as the pulse duration increased and those at the pulse duration of 4 seconds, which might be maximal in clinical practice, were approximately 1 mm. As an in vivo study, APC was applied over mucosal defects immediately after EMR. Only subtle tissue damage was observed even at the pulse duration of 20 seconds as shown in the ex vivo study. APC can be performed safely over the mucosal defects during/after EMR.

Original language	English
Pages (from-to)	137-140
Number of pages	4
Journal	Surgical Laparoscopy, Endoscopy and Percutaneous Techniques
Volume	16
Issue number	3
DOIs	https://doi.org/10.1097/00129689-200606000-00003
Publication status	Published - 2006 Jun 1

Fingerprint

Keywords

Argon plasma coagulation
Endoscopic mucosal resection
Hemostasis
Tissue damage

ASJC Scopus subject areas

Surgery

Cite this

Fujishiro, M., Yahagi, N., Nakamura, M., Kakushima, N., Kodashima, S., Ono, S., Kobayashi, K., Hashimoto, T., Yamamichi, N., Tateishi, A., Shimizu, Y., Oka, M., Ichinose, M., & Omata, M. (2006). Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, 16(3), 137-140. https://doi.org/10.1097/00129689-200606000-00003

Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection. / Fujishiro, Mitsuhiro; Yahagi, Naohisa; Nakamura, Masanori; Kakushima, Naomi; Kodashima, Shinya; Ono, Satoshi; Kobayashi, Katsuya; Hashimoto, Takuhei; Yamamichi, Nobutake; Tateishi, Ayako; Shimizu, Yasuhito; Oka, Masashi; Ichinose, Masao; Omata, Masao.

In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, Vol. 16, No. 3, 01.06.2006, p. 137-140.

Research output: Contribution to journal › Article

Fujishiro, M, Yahagi, N, Nakamura, M, Kakushima, N, Kodashima, S, Ono, S, Kobayashi, K, Hashimoto, T, Yamamichi, N, Tateishi, A, Shimizu, Y, Oka, M, Ichinose, M & Omata, M 2006, 'Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection', Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, vol. 16, no. 3, pp. 137-140. https://doi.org/10.1097/00129689-200606000-00003

Fujishiro, Mitsuhiro ; Yahagi, Naohisa ; Nakamura, Masanori ; Kakushima, Naomi ; Kodashima, Shinya ; Ono, Satoshi ; Kobayashi, Katsuya ; Hashimoto, Takuhei ; Yamamichi, Nobutake ; Tateishi, Ayako ; Shimizu, Yasuhito ; Oka, Masashi ; Ichinose, Masao ; Omata, Masao. / Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection. In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 2006 ; Vol. 16, No. 3. pp. 137-140.

@article{71fa64b07dfb40a9bd1c2d5effba15dc,

title = "Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection",

abstract = "Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline injection and without injection. Only subtle tissue damage was observed in the injection group, whereas apparent damage was observed in the noninjection group. The damaged distances in depth significantly increased as the pulse duration increased and those at the pulse duration of 4 seconds, which might be maximal in clinical practice, were approximately 1 mm. As an in vivo study, APC was applied over mucosal defects immediately after EMR. Only subtle tissue damage was observed even at the pulse duration of 20 seconds as shown in the ex vivo study. APC can be performed safely over the mucosal defects during/after EMR.",

keywords = "Argon plasma coagulation, Endoscopic mucosal resection, Hemostasis, Tissue damage",

author = "Mitsuhiro Fujishiro and Naohisa Yahagi and Masanori Nakamura and Naomi Kakushima and Shinya Kodashima and Satoshi Ono and Katsuya Kobayashi and Takuhei Hashimoto and Nobutake Yamamichi and Ayako Tateishi and Yasuhito Shimizu and Masashi Oka and Masao Ichinose and Masao Omata",

year = "2006",

month = jun

day = "1",

doi = "10.1097/00129689-200606000-00003",

language = "English",

volume = "16",

pages = "137--140",

journal = "Surgical Laparoscopy, Endoscopy and Percutaneous Techniques",

issn = "1530-4515",

publisher = "Lippincott Williams and Wilkins",

number = "3",

}

TY - JOUR

T1 - Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection

AU - Fujishiro, Mitsuhiro

AU - Yahagi, Naohisa

AU - Nakamura, Masanori

AU - Kakushima, Naomi

AU - Kodashima, Shinya

AU - Ono, Satoshi

AU - Kobayashi, Katsuya

AU - Hashimoto, Takuhei

AU - Yamamichi, Nobutake

AU - Tateishi, Ayako

AU - Shimizu, Yasuhito

AU - Oka, Masashi

AU - Ichinose, Masao

AU - Omata, Masao

PY - 2006/6/1

Y1 - 2006/6/1

N2 - Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline injection and without injection. Only subtle tissue damage was observed in the injection group, whereas apparent damage was observed in the noninjection group. The damaged distances in depth significantly increased as the pulse duration increased and those at the pulse duration of 4 seconds, which might be maximal in clinical practice, were approximately 1 mm. As an in vivo study, APC was applied over mucosal defects immediately after EMR. Only subtle tissue damage was observed even at the pulse duration of 20 seconds as shown in the ex vivo study. APC can be performed safely over the mucosal defects during/after EMR.

AB - Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline injection and without injection. Only subtle tissue damage was observed in the injection group, whereas apparent damage was observed in the noninjection group. The damaged distances in depth significantly increased as the pulse duration increased and those at the pulse duration of 4 seconds, which might be maximal in clinical practice, were approximately 1 mm. As an in vivo study, APC was applied over mucosal defects immediately after EMR. Only subtle tissue damage was observed even at the pulse duration of 20 seconds as shown in the ex vivo study. APC can be performed safely over the mucosal defects during/after EMR.

KW - Argon plasma coagulation

KW - Endoscopic mucosal resection

KW - Hemostasis

KW - Tissue damage

UR - http://www.scopus.com/inward/record.url?scp=33748145103&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748145103&partnerID=8YFLogxK

U2 - 10.1097/00129689-200606000-00003

DO - 10.1097/00129689-200606000-00003

M3 - Article

C2 - 16804454

AN - SCOPUS:33748145103

VL - 16

SP - 137

EP - 140

JO - Surgical Laparoscopy, Endoscopy and Percutaneous Techniques

JF - Surgical Laparoscopy, Endoscopy and Percutaneous Techniques

SN - 1530-4515

IS - 3

ER -

Access to Document

10.1097/00129689-200606000-00003