Safety of Daiobotampito in the Treatment of Acute Diverticulitis of the Colon: A Single-Center, Open-Label, Prospective Trial

Hiroshi Koike, Atsushi Nakazawa, Yuko Horiba, Nobuhiro Tsukada, Kenji Watanabe

Research output: Contribution to journalArticle


Purpose: The purpose of this study was to investigate the safety of daiobotampito in the treatment of acute diverticulitis of the colon. Methods: We conducted a single-center, open-label, prospective study. Ten patients who suffered from diverticulitis of the colon were recruited. The patients were treated with fasting, antibacterial agents, and daiobotampito extract for 10 days in or out of hospital. The patients individually recorded their body temperature, grade of abdominal pain, number of times that analgesics were used, and number of stools daily. We checked whether the patients had adverse reactions such as abdominal pain or diarrhea. Results: No patients experienced serious adverse reactions. One patient had moderate abdominal pain and diarrhea soon after daiobotampito intake. This patient discontinued daiobotampito on day 4, and the pain and diarrhea quickly resolved. The abdominal pain of this patient was worse 6 days before treatment, and the pain was almost relieved with initial daiobotampito treatment. Conclusions: Daiobotampito is a safe treatment option for early stage, acute diverticulitis.

Original languageEnglish
Pages (from-to)885-889
Number of pages5
JournalJournal of Alternative and Complementary Medicine
Issue number11
Publication statusPublished - 2017 Nov 1



  • daiobotampito
  • Kampo medicine
  • phase II trial
  • safety

ASJC Scopus subject areas

  • Complementary and alternative medicine

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