Saquayamycins, new aquayamycin-group antibiotics

T. Uchida, Masaya Imoto, Y. Watanabe, K. Miura, T. Dobashi, N. Matsuda, T. Sawa, H. Naganawa, M. Hamada, T. Takeuchi

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

From the culture broth of Streptomyces nodosus MH190-16F3, four new antibiotics have been isolated, and named saquayamycins A, B, C and D. The compounds are glycosides of aquayamycin, and among aquayamycin-group antibiotics they are most closely related to P-1894B (vineomycin A1). All saquayamycins act on Gram-positive bacteria and inhibit the growth of adriamycin-sensitive and adriamycin-resistant P388 leukemia cells.

Original languageEnglish
Pages (from-to)1171-1181
Number of pages11
JournalJournal of Antibiotics
Volume38
Issue number9
Publication statusPublished - 1985
Externally publishedYes

Fingerprint

Doxorubicin
Leukemia P388
Anti-Bacterial Agents
Streptomyces
Gram-Positive Bacteria
Glycosides
Growth
vineomycin A1
aquayamycin
saquayamycin
saquayamycin B
saquayamycin D

ASJC Scopus subject areas

  • Pharmacology
  • Molecular Medicine

Cite this

Uchida, T., Imoto, M., Watanabe, Y., Miura, K., Dobashi, T., Matsuda, N., ... Takeuchi, T. (1985). Saquayamycins, new aquayamycin-group antibiotics. Journal of Antibiotics, 38(9), 1171-1181.

Saquayamycins, new aquayamycin-group antibiotics. / Uchida, T.; Imoto, Masaya; Watanabe, Y.; Miura, K.; Dobashi, T.; Matsuda, N.; Sawa, T.; Naganawa, H.; Hamada, M.; Takeuchi, T.

In: Journal of Antibiotics, Vol. 38, No. 9, 1985, p. 1171-1181.

Research output: Contribution to journalArticle

Uchida, T, Imoto, M, Watanabe, Y, Miura, K, Dobashi, T, Matsuda, N, Sawa, T, Naganawa, H, Hamada, M & Takeuchi, T 1985, 'Saquayamycins, new aquayamycin-group antibiotics', Journal of Antibiotics, vol. 38, no. 9, pp. 1171-1181.
Uchida T, Imoto M, Watanabe Y, Miura K, Dobashi T, Matsuda N et al. Saquayamycins, new aquayamycin-group antibiotics. Journal of Antibiotics. 1985;38(9):1171-1181.
Uchida, T. ; Imoto, Masaya ; Watanabe, Y. ; Miura, K. ; Dobashi, T. ; Matsuda, N. ; Sawa, T. ; Naganawa, H. ; Hamada, M. ; Takeuchi, T. / Saquayamycins, new aquayamycin-group antibiotics. In: Journal of Antibiotics. 1985 ; Vol. 38, No. 9. pp. 1171-1181.
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AU - Matsuda, N.

AU - Sawa, T.

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