Scanning laser microscope able to detect the refraction of the laser beam

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6 Citations (Scopus)

Abstract

We have developed a scanning laser microscope system that can measure the spatial inhomogeneity of the refractive index using the laser beam refracted by the sample. Using this microscope, we can observe samples which are nearly transparent, such as live cells, without any use of dyes. Furthermore, we have visualized the Brownian motion of cell structures by detecting random fluctuations in the photoelectric current. This allows us to understand the rigidity of cell structures and the mobility within them.

Original languageEnglish
Pages (from-to)3279-3282
Number of pages4
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Volume44
Issue number5 A
DOIs
Publication statusPublished - 2005 May 1

Keywords

  • Brownian motion
  • Cell
  • Laser microscope
  • Quadrant photodiodes
  • Refractive index

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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