Abstract
Hot water extracts of 160 crude drugs used in Nepal were tested for their in vitro nematocidal activity on the second-stage larva of the dog roundworm, Toxocara cains, which is a common pathogenic parasite in larva migrans. Twenty-two of them showed a potent nematocidal activity (RM = 0, after 24 h incubation), and the activities of ''Bojho'' (rhizome of Acorus calamus L.) and ''Pan ko Jara'' (rhizome of Alpinia galanga SWARTZ) were particularly strong (RM = 0, after 6 h incubation). The active principle of Pan ko Jara was identified as [S]-1'-acetoxychavicol acetate.
| Original language | English |
|---|---|
| Pages (from-to) | 294-299 |
| Number of pages | 6 |
| Journal | Japanese Journal of Pharmacognosy |
| Volume | 43 |
| Issue number | 4 |
| Publication status | Published - 1989 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology
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Screening of crude drugs used in Nepal for nematocidal activity on the larva of toxocara canis. / Kiuchi, Fumiyuki; Hayashi, M.; Nakamura, N.; Mikage, M.; Tsuda, Y.; Kondo, K.; Namba, T.
In: Japanese Journal of Pharmacognosy, Vol. 43, No. 4, 1989, p. 294-299.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Screening of crude drugs used in Nepal for nematocidal activity on the larva of toxocara canis
AU - Kiuchi, Fumiyuki
AU - Hayashi, M.
AU - Nakamura, N.
AU - Mikage, M.
AU - Tsuda, Y.
AU - Kondo, K.
AU - Namba, T.
PY - 1989
Y1 - 1989
N2 - Hot water extracts of 160 crude drugs used in Nepal were tested for their in vitro nematocidal activity on the second-stage larva of the dog roundworm, Toxocara cains, which is a common pathogenic parasite in larva migrans. Twenty-two of them showed a potent nematocidal activity (RM = 0, after 24 h incubation), and the activities of ''Bojho'' (rhizome of Acorus calamus L.) and ''Pan ko Jara'' (rhizome of Alpinia galanga SWARTZ) were particularly strong (RM = 0, after 6 h incubation). The active principle of Pan ko Jara was identified as [S]-1'-acetoxychavicol acetate.
AB - Hot water extracts of 160 crude drugs used in Nepal were tested for their in vitro nematocidal activity on the second-stage larva of the dog roundworm, Toxocara cains, which is a common pathogenic parasite in larva migrans. Twenty-two of them showed a potent nematocidal activity (RM = 0, after 24 h incubation), and the activities of ''Bojho'' (rhizome of Acorus calamus L.) and ''Pan ko Jara'' (rhizome of Alpinia galanga SWARTZ) were particularly strong (RM = 0, after 6 h incubation). The active principle of Pan ko Jara was identified as [S]-1'-acetoxychavicol acetate.
UR - http://www.scopus.com/inward/record.url?scp=0024782155&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024782155&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0024782155
VL - 43
SP - 294
EP - 299
JO - Journal of Natural Medicines
JF - Journal of Natural Medicines
SN - 1861-0293
IS - 4
ER -