Abstract
Hot water extracts of 160 crude drugs used in Nepal were tested for their in vitro nematocidal activity on the second-stage larva of the dog roundworm, Toxocara cains, which is a common pathogenic parasite in larva migrans. Twenty-two of them showed a potent nematocidal activity (RM = 0, after 24 h incubation), and the activities of ''Bojho'' (rhizome of Acorus calamus L.) and ''Pan ko Jara'' (rhizome of Alpinia galanga SWARTZ) were particularly strong (RM = 0, after 6 h incubation). The active principle of Pan ko Jara was identified as [S]-1'-acetoxychavicol acetate.
Original language | English |
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Pages (from-to) | 294-299 |
Number of pages | 6 |
Journal | Japanese Journal of Pharmacognosy |
Volume | 43 |
Issue number | 4 |
Publication status | Published - 1989 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology