Hot water extracts of 160 crude drugs used in Nepal were tested for their in vitro nematocidal activity on the second-stage larva of the dog roundworm, Toxocara cains, which is a common pathogenic parasite in larva migrans. Twenty-two of them showed a potent nematocidal activity (RM = 0, after 24 h incubation), and the activities of ''Bojho'' (rhizome of Acorus calamus L.) and ''Pan ko Jara'' (rhizome of Alpinia galanga SWARTZ) were particularly strong (RM = 0, after 6 h incubation). The active principle of Pan ko Jara was identified as [S]-1'-acetoxychavicol acetate.
|Number of pages||6|
|Journal||Japanese Journal of Pharmacognosy|
|Publication status||Published - 1989|
ASJC Scopus subject areas
- Molecular Medicine