Screening of crude drugs used in Turkey for nematocidal activity on the larva of Toxocara canis

F. Kiuchi, N. Koshimaru, Y. Tsuda, K. Kondo, M. Tabata, G. Honda

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Water and methanol extracts of 84 traditional medicines collected in Turkey were tested for their nematocidal activity on the second-stage larva of Toxocara canis. A significant nematocidal activity (RM < 30) was found in 22 water extracts at a concentration of 10 mg/ml and in 25 methanol extracts at 1 mg/ml. The methanol extracts of havlican kok (Alpinia officinarum HANCE), casir koku (Ferula meifolia BOISS.), darifulful (Piper longum L.), and tarcin (Cinnamomum verum J.S. PRESL.) were active even at a concentration as low as 0.1-0.2 mg/ml. Active principles in some of the above medicines were further investigated.

Original languageEnglish
Pages (from-to)353-359
Number of pages7
JournalJapanese Journal of Pharmacognosy
Volume43
Issue number4
Publication statusPublished - 1989 Dec 1
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology

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