Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi

Fumiyuki Kiuchi; Kenji Matsuo; Yoshiaki Itano; Michiho Ito; Gisho Honda; Tran Kim Qui; Junko Nakajima-Shimada; Takashi Aoki

Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi

Fumiyuki Kiuchi, Kenji Matsuo, Yoshiaki Itano, Michiho Ito, Gisho Honda, Tran Kim Qui, Junko Nakajima-Shimada, Takashi Aoki

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Acetone, MeOH, and water extracts of 90 natural medicines used in Vietnam were tested for their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the causative agent of Chagas' disease. Strong trypanocidal activity was found in the acetone extracts of 7 natural medicines, i.e. chân bâu (Combretum quadrangulare), khô sâm bāc (Sophora flavescens), by lá môt hoa (Paris polyphylla), cao luong khuong (Alpinia galanga), hāc huong (Pogostemon cablin), màn kinh tu(Vitex trifolia), thach hôc (Dendrobium nobile). l'-Acetoxychavicol acetate (1) and related phenylpropanoids were identified as the trypanocidal constituents of cao luong khuong.

Original language	English
Pages (from-to)	64-68
Number of pages	5
Journal	Natural Medicines
Volume	56
Issue number	2
Publication status	Published - 2002 Jan 1
Externally published	Yes

Keywords

Alpinia galanga
Epimastigote
Natural medicine
Trypanocidal activity
Trypanosoma cruzi
Vietnam

ASJC Scopus subject areas

Molecular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi",

abstract = "Acetone, MeOH, and water extracts of 90 natural medicines used in Vietnam were tested for their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the causative agent of Chagas' disease. Strong trypanocidal activity was found in the acetone extracts of 7 natural medicines, i.e. ch{\^a}n b{\^a}u (Combretum quadrangulare), kh{\^o} s{\^a}m bāc (Sophora flavescens), by l{\'a} m{\^o}t hoa (Paris polyphylla), cao luong khuong (Alpinia galanga), hāc huong (Pogostemon cablin), m{\`a}n kinh tu(Vitex trifolia), thach h{\^o}c (Dendrobium nobile). l'-Acetoxychavicol acetate (1) and related phenylpropanoids were identified as the trypanocidal constituents of cao luong khuong.",

keywords = "Alpinia galanga, Epimastigote, Natural medicine, Trypanocidal activity, Trypanosoma cruzi, Vietnam",

author = "Fumiyuki Kiuchi and Kenji Matsuo and Yoshiaki Itano and Michiho Ito and Gisho Honda and Qui, {Tran Kim} and Junko Nakajima-Shimada and Takashi Aoki",

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AU - Kiuchi, Fumiyuki

AU - Matsuo, Kenji

AU - Itano, Yoshiaki

AU - Ito, Michiho

AU - Honda, Gisho

AU - Qui, Tran Kim

AU - Nakajima-Shimada, Junko

AU - Aoki, Takashi

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Acetone, MeOH, and water extracts of 90 natural medicines used in Vietnam were tested for their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the causative agent of Chagas' disease. Strong trypanocidal activity was found in the acetone extracts of 7 natural medicines, i.e. chân bâu (Combretum quadrangulare), khô sâm bāc (Sophora flavescens), by lá môt hoa (Paris polyphylla), cao luong khuong (Alpinia galanga), hāc huong (Pogostemon cablin), màn kinh tu(Vitex trifolia), thach hôc (Dendrobium nobile). l'-Acetoxychavicol acetate (1) and related phenylpropanoids were identified as the trypanocidal constituents of cao luong khuong.

AB - Acetone, MeOH, and water extracts of 90 natural medicines used in Vietnam were tested for their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the causative agent of Chagas' disease. Strong trypanocidal activity was found in the acetone extracts of 7 natural medicines, i.e. chân bâu (Combretum quadrangulare), khô sâm bāc (Sophora flavescens), by lá môt hoa (Paris polyphylla), cao luong khuong (Alpinia galanga), hāc huong (Pogostemon cablin), màn kinh tu(Vitex trifolia), thach hôc (Dendrobium nobile). l'-Acetoxychavicol acetate (1) and related phenylpropanoids were identified as the trypanocidal constituents of cao luong khuong.

KW - Alpinia galanga

KW - Epimastigote

KW - Natural medicine

KW - Trypanocidal activity

KW - Trypanosoma cruzi

KW - Vietnam

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SN - 1861-0293

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ER -

Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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