Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi

Fumiyuki Kiuchi, Kenji Matsuo, Yoshiaki Itano, Michiho Ito, Gisho Honda, Tran Kim Qui, Junko Nakajima-Shimada, Takashi Aoki

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Acetone, MeOH, and water extracts of 90 natural medicines used in Vietnam were tested for their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the causative agent of Chagas' disease. Strong trypanocidal activity was found in the acetone extracts of 7 natural medicines, i.e. chân bâu (Combretum quadrangulare), khô sâm bāc (Sophora flavescens), by lá môt hoa (Paris polyphylla), cao luong khuong (Alpinia galanga), hāc huong (Pogostemon cablin), màn kinh tu(Vitex trifolia), thach hôc (Dendrobium nobile). l'-Acetoxychavicol acetate (1) and related phenylpropanoids were identified as the trypanocidal constituents of cao luong khuong.

Original languageEnglish
Pages (from-to)64-68
Number of pages5
JournalNatural Medicines
Volume56
Issue number2
Publication statusPublished - 2002
Externally publishedYes

Fingerprint

Vietnam
Trypanosoma cruzi
Acetone
Medicine
Combretum
Screening
Dendrobium
Alpinia
Vitex
Sophora
Trifolium
Chagas Disease
Paris
Water
Pogostemon
1'-acetoxychavicol acetate

Keywords

  • Alpinia galanga
  • Epimastigote
  • Natural medicine
  • Trypanocidal activity
  • Trypanosoma cruzi
  • Vietnam

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Kiuchi, F., Matsuo, K., Itano, Y., Ito, M., Honda, G., Qui, T. K., ... Aoki, T. (2002). Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi. Natural Medicines, 56(2), 64-68.

Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi. / Kiuchi, Fumiyuki; Matsuo, Kenji; Itano, Yoshiaki; Ito, Michiho; Honda, Gisho; Qui, Tran Kim; Nakajima-Shimada, Junko; Aoki, Takashi.

In: Natural Medicines, Vol. 56, No. 2, 2002, p. 64-68.

Research output: Contribution to journalArticle

Kiuchi, F, Matsuo, K, Itano, Y, Ito, M, Honda, G, Qui, TK, Nakajima-Shimada, J & Aoki, T 2002, 'Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi', Natural Medicines, vol. 56, no. 2, pp. 64-68.
Kiuchi, Fumiyuki ; Matsuo, Kenji ; Itano, Yoshiaki ; Ito, Michiho ; Honda, Gisho ; Qui, Tran Kim ; Nakajima-Shimada, Junko ; Aoki, Takashi. / Screening of natural medicines used in Vietnam for trypanocidal activity against epimastigotes of Trypanosoma cruzi. In: Natural Medicines. 2002 ; Vol. 56, No. 2. pp. 64-68.
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