Secondary Metabolites with New Medicinal Functions from Marine Organisms

Osamu Ohno, Kiyotake Suenaga, Daisuke Uemura

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

We have focused on the identification of natural key compounds that possess biologically and medicinally intriguing functions. Some of bioactive naturally occurring compounds isolated from marine organisms were found to possess unique biological activities. Halichlorine from the marine sponge Halichondria okadai was shown to inhibit the activity of nuclear factor-κB in endothelial cells and block L-type Ca 2+ channels. Thus, it may have therapeutic potentials for diseases such as atherosclerosis and hypertension.

Original languageEnglish
Title of host publicationAdvances in Food and Nutrition Research
PublisherAcademic Press Inc.
Pages185-193
Number of pages9
DOIs
Publication statusPublished - 2012

Publication series

NameAdvances in Food and Nutrition Research
Volume65
ISSN (Print)1043-4526

    Fingerprint

Keywords

  • Atherosclerosis
  • Halichlorine
  • Marine organisms
  • Secondary metabolites

ASJC Scopus subject areas

  • Food Science

Cite this

Ohno, O., Suenaga, K., & Uemura, D. (2012). Secondary Metabolites with New Medicinal Functions from Marine Organisms. In Advances in Food and Nutrition Research (pp. 185-193). (Advances in Food and Nutrition Research; Vol. 65). Academic Press Inc.. https://doi.org/10.1016/B978-0-12-416003-3.00011-1