Secular trends and geographical variations in the dietary intake of polybrominated diphenyl ethers (PBDEs) using archived samples from the early 1980s and mid 1990s in Japan

Yasuhiko Wada, Akio Koizumi, Takeo Yoshinaga, Kouji Harada, Kayoko Inoue, Akiko Morikawa, Junko Muroi, Sumiko Inoue, Bita Eslami, Iwao Hirosawa, Akitsu Hirosawa, Shigeo Fujii, Yoshinori Fujimine, Noriyuki Hachiya, Shigeki Koda, Yukinori Kusaka, Katsuyuki Murata, Haruo Nakatsuka, Kazuyuki Omae, Norimitsu SaitoShinichiro Shimbo, Katsunobu Takenaka, Tatsuya Takeshita, Hidemi Todoriki, Takao Watanabe, Masayuki Ikeda

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A retrospective exposure assessment among the general population for polybrominated diphenyl ethers (PBDEs) was conducted using dietary surveys. We analyzed samples of food duplicate portions collected in the early 1980s (1980 survey: N=40) and the mid 1990s (1995 survey: N=39) from female subjects (5 participants from each of 8 sites per survey except for one site) living throughout Japan, from the north (Hokkaido) to the south (Okinawa). The study populations in the 1980 and 1995 surveys were different, but lived in the same communities. We measured four PBDE congeners [2,2',4,4'-tetrabrominated diphenyl ether (tetraBDE): #47; 2,2',4,4',5-pentaBDE: #99; 2,2',4,4',6-pentaBDE: #100; and 2,2',4,4',5,5'-hexaBDE: #153] in the diet. #99 was the most abundant congener in the diet (49% of the total PBDEs), followed by #47 (33%), #100 (12%) and #153 (6%). Regional variations found in the 1980 survey decreased in the 1995 survey. The total daily intake of PBDEs (ng/d) [GM (GSD)] in the 1980 survey [91.4 (4.1)] was not significantly different from that in the 1995 survey [93.8 (3.4)] for the total population, nor did it differ among the sites including Shimane, in which a 20-fold increase in serum concentrations was observed in the same population. In consideration of the significant increases in the serum concentration, inhalation may be more important than food ingestion as the route of human exposure to PBDEs.

Original languageEnglish
Pages (from-to)236-241
Number of pages6
JournalJournal of Occupational Health
Volume47
Issue number3
DOIs
Publication statusPublished - 2005 May

Fingerprint

Halogenated Diphenyl Ethers
Japan
Nutrition
Population
Diet
Surveys and Questionnaires
Food
Serum
Inhalation
Eating

Keywords

  • Congener pattern
  • Exposure
  • Food
  • Polybrominated diphenyl ethers
  • Regional variation
  • Retrospective study
  • Sample bank

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Toxicology

Cite this

Secular trends and geographical variations in the dietary intake of polybrominated diphenyl ethers (PBDEs) using archived samples from the early 1980s and mid 1990s in Japan. / Wada, Yasuhiko; Koizumi, Akio; Yoshinaga, Takeo; Harada, Kouji; Inoue, Kayoko; Morikawa, Akiko; Muroi, Junko; Inoue, Sumiko; Eslami, Bita; Hirosawa, Iwao; Hirosawa, Akitsu; Fujii, Shigeo; Fujimine, Yoshinori; Hachiya, Noriyuki; Koda, Shigeki; Kusaka, Yukinori; Murata, Katsuyuki; Nakatsuka, Haruo; Omae, Kazuyuki; Saito, Norimitsu; Shimbo, Shinichiro; Takenaka, Katsunobu; Takeshita, Tatsuya; Todoriki, Hidemi; Watanabe, Takao; Ikeda, Masayuki.

In: Journal of Occupational Health, Vol. 47, No. 3, 05.2005, p. 236-241.

Research output: Contribution to journalArticle

Wada, Y, Koizumi, A, Yoshinaga, T, Harada, K, Inoue, K, Morikawa, A, Muroi, J, Inoue, S, Eslami, B, Hirosawa, I, Hirosawa, A, Fujii, S, Fujimine, Y, Hachiya, N, Koda, S, Kusaka, Y, Murata, K, Nakatsuka, H, Omae, K, Saito, N, Shimbo, S, Takenaka, K, Takeshita, T, Todoriki, H, Watanabe, T & Ikeda, M 2005, 'Secular trends and geographical variations in the dietary intake of polybrominated diphenyl ethers (PBDEs) using archived samples from the early 1980s and mid 1990s in Japan', Journal of Occupational Health, vol. 47, no. 3, pp. 236-241. https://doi.org/10.1539/joh.47.236
Wada, Yasuhiko ; Koizumi, Akio ; Yoshinaga, Takeo ; Harada, Kouji ; Inoue, Kayoko ; Morikawa, Akiko ; Muroi, Junko ; Inoue, Sumiko ; Eslami, Bita ; Hirosawa, Iwao ; Hirosawa, Akitsu ; Fujii, Shigeo ; Fujimine, Yoshinori ; Hachiya, Noriyuki ; Koda, Shigeki ; Kusaka, Yukinori ; Murata, Katsuyuki ; Nakatsuka, Haruo ; Omae, Kazuyuki ; Saito, Norimitsu ; Shimbo, Shinichiro ; Takenaka, Katsunobu ; Takeshita, Tatsuya ; Todoriki, Hidemi ; Watanabe, Takao ; Ikeda, Masayuki. / Secular trends and geographical variations in the dietary intake of polybrominated diphenyl ethers (PBDEs) using archived samples from the early 1980s and mid 1990s in Japan. In: Journal of Occupational Health. 2005 ; Vol. 47, No. 3. pp. 236-241.
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abstract = "A retrospective exposure assessment among the general population for polybrominated diphenyl ethers (PBDEs) was conducted using dietary surveys. We analyzed samples of food duplicate portions collected in the early 1980s (1980 survey: N=40) and the mid 1990s (1995 survey: N=39) from female subjects (5 participants from each of 8 sites per survey except for one site) living throughout Japan, from the north (Hokkaido) to the south (Okinawa). The study populations in the 1980 and 1995 surveys were different, but lived in the same communities. We measured four PBDE congeners [2,2',4,4'-tetrabrominated diphenyl ether (tetraBDE): #47; 2,2',4,4',5-pentaBDE: #99; 2,2',4,4',6-pentaBDE: #100; and 2,2',4,4',5,5'-hexaBDE: #153] in the diet. #99 was the most abundant congener in the diet (49{\%} of the total PBDEs), followed by #47 (33{\%}), #100 (12{\%}) and #153 (6{\%}). Regional variations found in the 1980 survey decreased in the 1995 survey. The total daily intake of PBDEs (ng/d) [GM (GSD)] in the 1980 survey [91.4 (4.1)] was not significantly different from that in the 1995 survey [93.8 (3.4)] for the total population, nor did it differ among the sites including Shimane, in which a 20-fold increase in serum concentrations was observed in the same population. In consideration of the significant increases in the serum concentration, inhalation may be more important than food ingestion as the route of human exposure to PBDEs.",
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AU - Yoshinaga, Takeo

AU - Harada, Kouji

AU - Inoue, Kayoko

AU - Morikawa, Akiko

AU - Muroi, Junko

AU - Inoue, Sumiko

AU - Eslami, Bita

AU - Hirosawa, Iwao

AU - Hirosawa, Akitsu

AU - Fujii, Shigeo

AU - Fujimine, Yoshinori

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AU - Koda, Shigeki

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AU - Murata, Katsuyuki

AU - Nakatsuka, Haruo

AU - Omae, Kazuyuki

AU - Saito, Norimitsu

AU - Shimbo, Shinichiro

AU - Takenaka, Katsunobu

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