Selective bindings of a lectin for phase-separated glycolipid monolayers

Mineo Hashizume, Toshinori Sato, Yoshio Okahata

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Phase separation was observed by measuring surface pressure (π)-area (A) isotherms of the mixed monolayer of lactosylceramide (LacCer) and dioleoylphosphatidylcholine (DOPC). Bindings of Allomyrina dichotoma (allo A) lectin to LacCer in mixed monolayers were measured by means of quartz-crystal microbalance (QCM) that was attached horizontally to the monolayers. Allo A showed the high binding affinity for the LacCer phase-separated in the DOPC monolayer, but showed the low binding affinity for the LacCer homogeneously mixed with dipalmikiylphosphatidylcholine (DPPC) matrix.

Original languageEnglish
Pages (from-to)399-400
Number of pages2
JournalChemistry Letters
Issue number5
Publication statusPublished - 1998
Externally publishedYes

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Glycolipids
Lectins
Monolayers
Quartz crystal microbalances
Phase separation
Isotherms
CDw17 antigen
1,2-oleoylphosphatidylcholine

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Selective bindings of a lectin for phase-separated glycolipid monolayers. / Hashizume, Mineo; Sato, Toshinori; Okahata, Yoshio.

In: Chemistry Letters, No. 5, 1998, p. 399-400.

Research output: Contribution to journalArticle

Hashizume, Mineo ; Sato, Toshinori ; Okahata, Yoshio. / Selective bindings of a lectin for phase-separated glycolipid monolayers. In: Chemistry Letters. 1998 ; No. 5. pp. 399-400.
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