TY - GEN
T1 - Self-folding cell origami
T2 - 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
AU - Kuribayashi-Shigetomi, K.
AU - Onoe, H.
AU - Takeuchi, S.
PY - 2012/5/7
Y1 - 2012/5/7
N2 - We use cell traction force (CTF) to self-fold flat microplates into diverse three-dimensional (3D) cell-laden microstructures (Figure 1). Cells were selectively cultured onto the flat microfabricated plates. Immediately after detaching the plates from the glass substrate, the plates were lifted and folded up into the 3D microstructures due to the CTF caused by stretched cells that adhered between two plates. We achieved precise folding angles between the folding microplate and glass substrate by producing a flexible joint between the plates. Using the microplates with the flexible joint, we also achieved batch process of self-folding 3D cell-laden microstructures. In addition, we succeed to produce micro-flapping structures using cardiomyocytes as an actuator.
AB - We use cell traction force (CTF) to self-fold flat microplates into diverse three-dimensional (3D) cell-laden microstructures (Figure 1). Cells were selectively cultured onto the flat microfabricated plates. Immediately after detaching the plates from the glass substrate, the plates were lifted and folded up into the 3D microstructures due to the CTF caused by stretched cells that adhered between two plates. We achieved precise folding angles between the folding microplate and glass substrate by producing a flexible joint between the plates. Using the microplates with the flexible joint, we also achieved batch process of self-folding 3D cell-laden microstructures. In addition, we succeed to produce micro-flapping structures using cardiomyocytes as an actuator.
UR - http://www.scopus.com/inward/record.url?scp=84860481695&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860481695&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2012.6170096
DO - 10.1109/MEMSYS.2012.6170096
M3 - Conference contribution
AN - SCOPUS:84860481695
SN - 9781467303248
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 72
EP - 75
BT - 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
Y2 - 29 January 2012 through 2 February 2012
ER -