Self-folding cell origami

Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force

K. Kuribayashi-Shigetomi, Hiroaki Onoe, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

We use cell traction force (CTF) to self-fold flat microplates into diverse three-dimensional (3D) cell-laden microstructures (Figure 1). Cells were selectively cultured onto the flat microfabricated plates. Immediately after detaching the plates from the glass substrate, the plates were lifted and folded up into the 3D microstructures due to the CTF caused by stretched cells that adhered between two plates. We achieved precise folding angles between the folding microplate and glass substrate by producing a flexible joint between the plates. Using the microplates with the flexible joint, we also achieved batch process of self-folding 3D cell-laden microstructures. In addition, we succeed to produce micro-flapping structures using cardiomyocytes as an actuator.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages72-75
Number of pages4
DOIs
Publication statusPublished - 2012
Externally publishedYes
Event2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 - Paris, France
Duration: 2012 Jan 292012 Feb 2

Other

Other2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
CountryFrance
CityParis
Period12/1/2912/2/2

Fingerprint

traction
folding
microstructure
Microstructure
cells
Glass
Substrates
flapping
Actuators
glass
flat plates
actuators

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Kuribayashi-Shigetomi, K., Onoe, H., & Takeuchi, S. (2012). Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 72-75). [6170096] https://doi.org/10.1109/MEMSYS.2012.6170096

Self-folding cell origami : Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. / Kuribayashi-Shigetomi, K.; Onoe, Hiroaki; Takeuchi, S.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2012. p. 72-75 6170096.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kuribayashi-Shigetomi, K, Onoe, H & Takeuchi, S 2012, Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)., 6170096, pp. 72-75, 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012, Paris, France, 12/1/29. https://doi.org/10.1109/MEMSYS.2012.6170096
Kuribayashi-Shigetomi K, Onoe H, Takeuchi S. Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2012. p. 72-75. 6170096 https://doi.org/10.1109/MEMSYS.2012.6170096
Kuribayashi-Shigetomi, K. ; Onoe, Hiroaki ; Takeuchi, S. / Self-folding cell origami : Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2012. pp. 72-75
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