Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force

K. Kuribayashi-Shigetomi; H. Onoe; S. Takeuchi

doi:10.1109/MEMSYS.2012.6170096

Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force

K. Kuribayashi-Shigetomi, H. Onoe, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Citations (Scopus)

Abstract

We use cell traction force (CTF) to self-fold flat microplates into diverse three-dimensional (3D) cell-laden microstructures (Figure 1). Cells were selectively cultured onto the flat microfabricated plates. Immediately after detaching the plates from the glass substrate, the plates were lifted and folded up into the 3D microstructures due to the CTF caused by stretched cells that adhered between two plates. We achieved precise folding angles between the folding microplate and glass substrate by producing a flexible joint between the plates. Using the microplates with the flexible joint, we also achieved batch process of self-folding 3D cell-laden microstructures. In addition, we succeed to produce micro-flapping structures using cardiomyocytes as an actuator.

Original language	English
Title of host publication	2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
Pages	72-75
Number of pages	4
DOIs	https://doi.org/10.1109/MEMSYS.2012.6170096
Publication status	Published - 2012 May 7
Externally published	Yes
Event	2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 - Paris, France Duration: 2012 Jan 29 → 2012 Feb 2

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Other

Other	2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
Country	France
City	Paris
Period	12/1/29 → 12/2/2

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

Access to Document

10.1109/MEMSYS.2012.6170096

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Kuribayashi-Shigetomi, K., Onoe, H., & Takeuchi, S. (2012). Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 (pp. 72-75). [6170096] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2012.6170096

Self-folding cell origami : Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. / Kuribayashi-Shigetomi, K.; Onoe, H.; Takeuchi, S.

2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012. 2012. p. 72-75 6170096 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kuribayashi-Shigetomi, K, Onoe, H & Takeuchi, S 2012, Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. in 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012., 6170096, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 72-75, 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012, Paris, France, 12/1/29. https://doi.org/10.1109/MEMSYS.2012.6170096

Kuribayashi-Shigetomi K, Onoe H, Takeuchi S. Self-folding cell origami: Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012. 2012. p. 72-75. 6170096. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2012.6170096

Kuribayashi-Shigetomi, K. ; Onoe, H. ; Takeuchi, S. / Self-folding cell origami : Batch process of self-folding 3D cell-laden microstructures actuated by cell traction force. 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012. 2012. pp. 72-75 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

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