Seroepidemiologic study of hepatitis B virus infection at San Juan district in the Republic of Bolivia

Yoshikazu Yonei, Hiromasa ISHii, Masatoshi Kusuhara, Shinzo Kato, Masaharu Tsuchiya, Go Wakabayashi, Toshiaki Kamiya

Research output: Contribution to journalArticle

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Abstract

The markers for hepatitis B virus including HBsAg and anti-HBs were determined in 484 sera obtained from 300 Japanese and 184 Bolivians living in the San Juan district in the Republic of Bolivia. In adults (older than 16 years old) HBsAg was detected in 7.1% of Japanese, but was not detected in Bolivians. As for anti-HBs, 45% of Japanese were positive, whereas 27% of Bolivian were positive. Among children (undre 16 years old), prevalence of HBsAg was 10% in Japanese and none in Bolivians, whereas anti-HBs were detected in 66% of Japanese and in 3.8% of Bolivians. Moreover, twenty six sera obtained from HBsAg positive subjects were tested for HBe antigen-antibody system by radioimmunoassay. In adults, 9.1% were positive for HBeAg, whereas 53% of children was HBeAg positive. Twenty five HBsAg-positive subjects were also tested for subtypes of HBsAg by hemagglutination inhibition method, revealing that 80% of HBsAg was subtype ‘adw’, and 20% of it was subtype ‘adr’.

Original languageEnglish
Pages (from-to)615-619
Number of pages5
JournalActa Hepatologica Japonica
Volume24
Issue number6
DOIs
Publication statusPublished - 1983

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Bolivia
Seroepidemiologic Studies
Virus Diseases
Hepatitis B Surface Antigens
Hepatitis B virus
Hepatitis B e Antigens
Hemagglutination
Serum
Radioimmunoassay
Antigens
Antibodies

ASJC Scopus subject areas

  • Hepatology

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Seroepidemiologic study of hepatitis B virus infection at San Juan district in the Republic of Bolivia. / Yonei, Yoshikazu; ISHii, Hiromasa; Kusuhara, Masatoshi; Kato, Shinzo; Tsuchiya, Masaharu; Wakabayashi, Go; Kamiya, Toshiaki.

In: Acta Hepatologica Japonica, Vol. 24, No. 6, 1983, p. 615-619.

Research output: Contribution to journalArticle

Yonei, Yoshikazu ; ISHii, Hiromasa ; Kusuhara, Masatoshi ; Kato, Shinzo ; Tsuchiya, Masaharu ; Wakabayashi, Go ; Kamiya, Toshiaki. / Seroepidemiologic study of hepatitis B virus infection at San Juan district in the Republic of Bolivia. In: Acta Hepatologica Japonica. 1983 ; Vol. 24, No. 6. pp. 615-619.
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