Serotonin and pancreatic duct function.

S. Naruse, A. Suzuki, H. Ishiguro, M. Kitagawa, S. B. Ko, T. Yoshikawa, A. Yamamoto, H. Hamada, T. Hayakawa

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

1. 5-HT inhibits spontaneous fluid secretion as well as stimulated secretion with secretin (cAMP mediated) or ACh (Ca2+ mediated) in the isolated guinea pig pancreatic ducts. 2. The inhibitory effect of 5-HT is reversible and is dependent on the concentration in the range 0.01-0.1 microM, which is much lower than those that affect intestinal motility and secretion. 3. The 5-HT3 receptor in duct cells appears to mediate the inhibitory effect of 5-HT. 4. [Ca2+]i is unlikely to mediate the inhibitory effect of 5-HT.

Original languageEnglish
Pages (from-to)S27-28
JournalJournal of Korean medical science
Volume15 Suppl
DOIs
Publication statusPublished - 2000 Aug

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Serotonin and pancreatic duct function.'. Together they form a unique fingerprint.

  • Cite this

    Naruse, S., Suzuki, A., Ishiguro, H., Kitagawa, M., Ko, S. B., Yoshikawa, T., Yamamoto, A., Hamada, H., & Hayakawa, T. (2000). Serotonin and pancreatic duct function. Journal of Korean medical science, 15 Suppl, S27-28. https://doi.org/10.3346/jkms.2000.15.S.S27