Abstract
We studied 7 cases of anal carcinoma associated with anal fistula, which were treated in our institute from January 1970 to September 1991. The patients consisted of 6 men and one woman with an average age of 59.1 years ranging from 43 to 77 years. The period from the onset of anal fistula to the diagnosis of carcinoma ranged from 4 to 47 years with a mean of 22.9 years. Their chief complaints were anal mucinous discharge and/or bleeding, anal pain, palpitation of perianal hard nodules and anal stenosis. All patients were treated by abdominoperineal resection consisting of 4 curative and 3 non-curative resections. Histological findings varied, with 3 mucinous and 3 well/moderately differentiated adenocarcinomas and one squamous cell carcinoma. Although 4 of the 7 cases were diagnosed at the first diagnostic trial, the repeated biopsies failed to reveal the cancer cells in the other 3 cases until the final diagnosis. We concluded that repeated diagnostic trials including extended excision of the fistula are required for patients who have a long history of anal fistula with mucinous discharge and hard nodules, to differentiate the onset of anal carcinoma.
| Original language | English |
|---|---|
| Pages (from-to) | 2055-2059 |
| Number of pages | 5 |
| Journal | the japanese journal of gastroenterological surgery |
| Volume | 25 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1992 |
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Keywords
- anal carcinoma
- anal fistula
- carcinoma associated with anal fistula
ASJC Scopus subject areas
- Surgery
- Gastroenterology
Cite this
Seven Cases of Anal Carcinoma Associated with Anal Fistula. / Kase, Suguru; Kodaira, Susumu; Teramoto, Tatsuo; Hisa, Kousei; Furukawa, Kazuo; Yamaguchi, Hiroshi; Shatari, Tomoo; Hasegawa, Hirotoshi; Kuo, Tson Hong; Nishibori, Hideki; Kitajima, Masaki; Mukai, Makio.
In: the japanese journal of gastroenterological surgery, Vol. 25, No. 7, 1992, p. 2055-2059.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Seven Cases of Anal Carcinoma Associated with Anal Fistula
AU - Kase, Suguru
AU - Kodaira, Susumu
AU - Teramoto, Tatsuo
AU - Hisa, Kousei
AU - Furukawa, Kazuo
AU - Yamaguchi, Hiroshi
AU - Shatari, Tomoo
AU - Hasegawa, Hirotoshi
AU - Kuo, Tson Hong
AU - Nishibori, Hideki
AU - Kitajima, Masaki
AU - Mukai, Makio
PY - 1992
Y1 - 1992
N2 - We studied 7 cases of anal carcinoma associated with anal fistula, which were treated in our institute from January 1970 to September 1991. The patients consisted of 6 men and one woman with an average age of 59.1 years ranging from 43 to 77 years. The period from the onset of anal fistula to the diagnosis of carcinoma ranged from 4 to 47 years with a mean of 22.9 years. Their chief complaints were anal mucinous discharge and/or bleeding, anal pain, palpitation of perianal hard nodules and anal stenosis. All patients were treated by abdominoperineal resection consisting of 4 curative and 3 non-curative resections. Histological findings varied, with 3 mucinous and 3 well/moderately differentiated adenocarcinomas and one squamous cell carcinoma. Although 4 of the 7 cases were diagnosed at the first diagnostic trial, the repeated biopsies failed to reveal the cancer cells in the other 3 cases until the final diagnosis. We concluded that repeated diagnostic trials including extended excision of the fistula are required for patients who have a long history of anal fistula with mucinous discharge and hard nodules, to differentiate the onset of anal carcinoma.
AB - We studied 7 cases of anal carcinoma associated with anal fistula, which were treated in our institute from January 1970 to September 1991. The patients consisted of 6 men and one woman with an average age of 59.1 years ranging from 43 to 77 years. The period from the onset of anal fistula to the diagnosis of carcinoma ranged from 4 to 47 years with a mean of 22.9 years. Their chief complaints were anal mucinous discharge and/or bleeding, anal pain, palpitation of perianal hard nodules and anal stenosis. All patients were treated by abdominoperineal resection consisting of 4 curative and 3 non-curative resections. Histological findings varied, with 3 mucinous and 3 well/moderately differentiated adenocarcinomas and one squamous cell carcinoma. Although 4 of the 7 cases were diagnosed at the first diagnostic trial, the repeated biopsies failed to reveal the cancer cells in the other 3 cases until the final diagnosis. We concluded that repeated diagnostic trials including extended excision of the fistula are required for patients who have a long history of anal fistula with mucinous discharge and hard nodules, to differentiate the onset of anal carcinoma.
KW - anal carcinoma
KW - anal fistula
KW - carcinoma associated with anal fistula
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UR - http://www.scopus.com/inward/citedby.url?scp=85004571503&partnerID=8YFLogxK
U2 - 10.5833/jjgs.25.2055
DO - 10.5833/jjgs.25.2055
M3 - Article
VL - 25
SP - 2055
EP - 2059
JO - Japanese Journal of Gastroenterological Surgery
JF - Japanese Journal of Gastroenterological Surgery
SN - 0386-9768
IS - 7
ER -