Abstract
A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).
Original language | English |
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Pages | 3933-3934 |
Number of pages | 2 |
Publication status | Published - 2006 Dec 1 |
Event | 55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: 2006 Sep 20 → 2006 Sep 22 |
Other
Other | 55th Society of Polymer Science Japan Symposium on Macromolecules |
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Country/Territory | Japan |
City | Toyama |
Period | 06/9/20 → 06/9/22 |
Keywords
- Hierarchical structural transitions
- Peptide amphiphiles
ASJC Scopus subject areas
- Engineering(all)