Abstract
A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).
| Original language | English |
|---|---|
| Title of host publication | Polymer Preprints, Japan |
| Pages | 3933-3934 |
| Number of pages | 2 |
| Volume | 55 |
| Edition | 2 |
| Publication status | Published - 2006 |
| Event | 55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: 2006 Sep 20 → 2006 Sep 22 |
Other
| Other | 55th Society of Polymer Science Japan Symposium on Macromolecules |
|---|---|
| Country | Japan |
| City | Toyama |
| Period | 06/9/20 → 06/9/22 |
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Keywords
- Hierarchical structural transitions
- Peptide amphiphiles
ASJC Scopus subject areas
- Engineering(all)
Cite this
Shear-induced structural transitions of peptide amphiphile. / Hotta, Atsushi; Shimada, Tomoko; Tirrell, Matthew.
Polymer Preprints, Japan. Vol. 55 2. ed. 2006. p. 3933-3934.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Shear-induced structural transitions of peptide amphiphile
AU - Hotta, Atsushi
AU - Shimada, Tomoko
AU - Tirrell, Matthew
PY - 2006
Y1 - 2006
N2 - A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).
AB - A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).
KW - Hierarchical structural transitions
KW - Peptide amphiphiles
UR - http://www.scopus.com/inward/record.url?scp=33846162295&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33846162295&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:33846162295
VL - 55
SP - 3933
EP - 3934
BT - Polymer Preprints, Japan
ER -