Shear-induced structural transitions of peptide amphiphile

Atsushi Hotta, Tomoko Shimada, Matthew Tirrell

Research output: Contribution to conferencePaper

Abstract

A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).

Original languageEnglish
Pages3933-3934
Number of pages2
Publication statusPublished - 2006 Dec 1
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period06/9/2006/9/22

Keywords

  • Hierarchical structural transitions
  • Peptide amphiphiles

ASJC Scopus subject areas

  • Engineering(all)

Fingerprint Dive into the research topics of 'Shear-induced structural transitions of peptide amphiphile'. Together they form a unique fingerprint.

  • Cite this

    Hotta, A., Shimada, T., & Tirrell, M. (2006). Shear-induced structural transitions of peptide amphiphile. 3933-3934. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.