Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation

Yasunobu Yamashita, Alan Biard, Kengo Hanaya, Mitsuru Shoji, Takeshi Sugai

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Wogonin and astringin were synthesized from inexpensive chrysin and piceid in short steps. The key feature of these syntheses is site-selective transformation. The target molecules were obtained in 27 and 62% yields from the starting materials, respectively.

Original languageEnglish
Pages (from-to)1279-1284
Number of pages6
JournalBioscience, Biotechnology and Biochemistry
Volume81
Issue number7
DOIs
Publication statusPublished - 2017 Jan 1

Keywords

  • Astringin
  • Hydroxylation
  • Site-selective acetylation
  • Site-selective deacetylation
  • Wogonin

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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